{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Noah L"],"funding":["This collaborative study with Sanofi was sponsored by University Hospital of Clermont-Ferrand, France. Sanofi provided the treatments and partial financial support to the study","University Hospital of Clermont-Ferrand, France"],"pagination":["1863"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9102162"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(9)"],"pubmed_abstract":["The effect of a combination of magnesium, vitamins B6, B9, B12, rhodiola and green tea/L-theanine (Mg-Teadiola) on stress was evaluated in chronically stressed, otherwise healthy individuals. Effects on stress-related quality-of-life parameters (sleep and perception of pain) were also explored. Adults with stress for ≥1 month, scoring ≥14 points on the Depression Anxiety Stress Scale (DASS)-42 questionnaire, were randomized (1:1) to receive oral Mg-Teadiola (n = 49) or a placebo (n = 51), for 28 days, with a follow-up assessment on Day 56 (NCT04391452). The primary endpoint was the change in the DASS-42 stress score from baseline to Day 28 with Mg-Teadiola versus placebo. The DASS-42 stress scores significantly decreased from baseline to Day 28 with Mg-Teadiola versus placebo (effect size,"],"journal":["Nutrients"],"pubmed_title":["Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study."],"pmcid":["PMC9102162"],"funding_grant_id":["NA"],"pubmed_authors":["Morel V","Bertin C","Duale C","Pereira B","Noah L","Macian N","Pouteau E","Pickering G"],"additional_accession":[]},"is_claimable":false,"name":"Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study.","description":"The effect of a combination of magnesium, vitamins B6, B9, B12, rhodiola and green tea/L-theanine (Mg-Teadiola) on stress was evaluated in chronically stressed, otherwise healthy individuals. Effects on stress-related quality-of-life parameters (sleep and perception of pain) were also explored. Adults with stress for ≥1 month, scoring ≥14 points on the Depression Anxiety Stress Scale (DASS)-42 questionnaire, were randomized (1:1) to receive oral Mg-Teadiola (n = 49) or a placebo (n = 51), for 28 days, with a follow-up assessment on Day 56 (NCT04391452). The primary endpoint was the change in the DASS-42 stress score from baseline to Day 28 with Mg-Teadiola versus placebo. The DASS-42 stress scores significantly decreased from baseline to Day 28 with Mg-Teadiola versus placebo (effect size,","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-05-08T03:09:55.922Z","creation":"2024-10-16T11:36:07.647Z"},"accession":"S-EPMC9102162","cross_references":{"pubmed":["35565828"],"doi":["10.3390/nu14091863"]}}