biostudies-literatureBican RNICHD NIH HHS261-267https://www.ebi.ac.uk/biostudies/studies/S-EPMC9102785biostudies-literatureUnknown34(2)<h4>Purpose</h4>This case report highlights the potential value of delivering a high-dose physical therapy (PT) intervention for a child with a neurodegenerative disease. We include developmental outcomes for a 23-month-old toddler with biallelic TBCD gene mutations following daily outpatient PT.<h4>Summary of key points</h4>The child had clinical improvements in gross and fine motor, cognition, expressive and receptive language, socioemotional, and adaptive behavior function as determined through Goal Attainment Scaling, Gross Motor Function Measure, and Bayley Scales of Infant and Toddler Development following daily PT intervention.<h4>Statement of conclusion and recommendations for clinical practice</h4>High-dose outpatient PT may be beneficial for a child with a neurodegenerative diseaPediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy AssociationDaily Outpatient Physical Therapy for a Toddler With a Neurodegenerative Disease: A Case Report.PMC9102785R01 HD083384Bican RFerrante RHeathcock JCByars MHendershot SLo WfalseDaily Outpatient Physical Therapy for a Toddler With a Neurodegenerative Disease: A Case Report.<h4>Purpose</h4>This case report highlights the potential value of delivering a high-dose physical therapy (PT) intervention for a child with a neurodegenerative disease. We include developmental outcomes for a 23-month-old toddler with biallelic TBCD gene mutations following daily outpatient PT.<h4>Summary of key points</h4>The child had clinical improvements in gross and fine motor, cognition, expressive and receptive language, socioemotional, and adaptive behavior function as determined through Goal Attainment Scaling, Gross Motor Function Measure, and Bayley Scales of Infant and Toddler Development following daily PT intervention.<h4>Statement of conclusion and recommendations for clinical practice</h4>High-dose outpatient PT may be beneficial for a child with a neurodegenerative disea2022-01-01T00:00:00Z2022 Apr2025-04-19T13:29:00.726Z2025-04-19T13:29:00.726ZS-EPMC91027853538546410.1097/PEP.000000000000088410.1097/pep.0000000000000884