biostudies-literatureUnknown11(9)Veltkamp C<h4>Background and purpose</h4>Chronic inflammatory bowel diseases (IBD) frequently affect extraintestinal organs including the liver. Since limited evidence suggests the presence of liver disease in IBD patients, we studied the frequency of hepatic steatosis and fibrosis in these patients and characterized disease-related factors.<h4>Methods</h4>In this retrospective, cross-sectional, hospital-based, single-center study, consecutive patients with Crohn's disease (CD) and ulcerative colitis (UC) were included who had undergone routine abdominal ultrasound including transhepatic elastography. Hepatic steatosis was diagnosed by hyperechogenicity on B-mode ultrasound and by measuring controlled attenuation parameter (CAP). Hepatic fibrosis was assumed if transhepatic elastography yielded a stJournal of clinical medicine2623https://www.ebi.ac.uk/biostudies/studies/S-EPMC9105667biostudies-literatureHepatic Steatosis and Fibrosis in Chronic Inflammatory Bowel Disease.PMC9105667Lan SWeiss KHKorompoki ESeitz HKVeltkamp CSchmidt HfalseHepatic Steatosis and Fibrosis in Chronic Inflammatory Bowel Disease.<h4>Background and purpose</h4>Chronic inflammatory bowel diseases (IBD) frequently affect extraintestinal organs including the liver. Since limited evidence suggests the presence of liver disease in IBD patients, we studied the frequency of hepatic steatosis and fibrosis in these patients and characterized disease-related factors.<h4>Methods</h4>In this retrospective, cross-sectional, hospital-based, single-center study, consecutive patients with Crohn's disease (CD) and ulcerative colitis (UC) were included who had undergone routine abdominal ultrasound including transhepatic elastography. Hepatic steatosis was diagnosed by hyperechogenicity on B-mode ultrasound and by measuring controlled attenuation parameter (CAP). Hepatic fibrosis was assumed if transhepatic elastography yielded a st2022-01-01T00:00:00Z2022 May2025-05-31T23:36:33.914Z2025-04-03T22:18:37.411ZS-EPMC91056673556674910.3390/jcm11092623