{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stokes WA"],"funding":["NCI NIH HHS"],"pagination":["e231-e237"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9106833"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(3)"],"pubmed_abstract":["<h4>Background</h4>Operability is both a crucial determinant in treatment selection and a potential confounder in analyses comparing surgery with non-surgical approaches such as stereotactic body radiotherapy (SBRT). We aimed to assess the association between operability status and intervention with post-treatment mortality in early-stage non-small cell lung cancer (NSCLC).<h4>Patients and methods</h4>We defined four groups of patients with cT1-T2N0M0 NSCLC diagnosed 2010 to 2014 from the National Cancer Database: SBRT patients deemed operable vs. inoperable and surgery patients receiving open vs. minimally-invasive approaches. Mortality rates at 30, 60, and 90 days post-treatment were calculated and compared.<h4>Results</h4>We abstracted 80,108 patients, 0.8% undergoing SBRT and operable,"],"journal":["Clinical lung cancer"],"pubmed_title":["Association of Operability With Post-Treatment Mortality in Early-Stage Non-Small Cell Lung Cancer."],"pmcid":["PMC9106833"],"funding_grant_id":["P30 CA138292"],"pubmed_authors":["Liu Y","Xiong N","Bradley JD","Rusthoven CG","Stokes WA","Tian S","Higgins KA","Moghanaki D"],"additional_accession":[]},"is_claimable":false,"name":"Association of Operability With Post-Treatment Mortality in Early-Stage Non-Small Cell Lung Cancer.","description":"<h4>Background</h4>Operability is both a crucial determinant in treatment selection and a potential confounder in analyses comparing surgery with non-surgical approaches such as stereotactic body radiotherapy (SBRT). We aimed to assess the association between operability status and intervention with post-treatment mortality in early-stage non-small cell lung cancer (NSCLC).<h4>Patients and methods</h4>We defined four groups of patients with cT1-T2N0M0 NSCLC diagnosed 2010 to 2014 from the National Cancer Database: SBRT patients deemed operable vs. inoperable and surgery patients receiving open vs. minimally-invasive approaches. Mortality rates at 30, 60, and 90 days post-treatment were calculated and compared.<h4>Results</h4>We abstracted 80,108 patients, 0.8% undergoing SBRT and operable,","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-19T13:31:18.87Z","creation":"2025-04-19T13:31:18.87Z"},"accession":"S-EPMC9106833","cross_references":{"pubmed":["35093293"],"doi":["10.1016/j.cllc.2021.12.012"]}}