{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Tian R"],"pubmed_abstract":["The GATA transcription factor <i>Pannier</i> is identified as the major regulatory gene in color pattern formation in the Asian multi-colored ladybird beetle (<i>Harmonia axyridis</i>). however, the mechanisms of <i>Pannier</i> in regulating melanin synthesis and development in <i>H. axyridis</i> remain elusive. In this study, we identified and characterized <i>Pannier</i> in <i>H. axyridis</i> (<i>HaPnr</i>) and showed it to have two alternative spliced variants named <i>HaPnr-α</i> and <i>HaPnr-β</i>. Analyses of developmental stage expression patterns revealed that <i>HaPnr</i>, <i>HaPnr-α</i> and <i>HaPnr-β</i> were constitutively expressed throughout all developmental stages. To examine the role of <i>HaPnr</i> in <i>H. axyridis</i> development, RNA interference was performed in late "],"journal":["Frontiers in physiology"],"pagination":["909258"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9110671"],"repository":["biostudies-literature"],"pubmed_title":["The Molecular Properties and Roles of <i>Pannier</i> in <i>Harmonia axyridis</i>'s Metamorphosis and Melanin Synthesis."],"pmcid":["PMC9110671"],"pubmed_authors":["Wu M","Zang L","Wang S","Xu Q","Tian R","Chen X","Xiao D"],"additional_accession":[]},"is_claimable":false,"name":"The Molecular Properties and Roles of <i>Pannier</i> in <i>Harmonia axyridis</i>'s Metamorphosis and Melanin Synthesis.","description":"The GATA transcription factor <i>Pannier</i> is identified as the major regulatory gene in color pattern formation in the Asian multi-colored ladybird beetle (<i>Harmonia axyridis</i>). however, the mechanisms of <i>Pannier</i> in regulating melanin synthesis and development in <i>H. axyridis</i> remain elusive. In this study, we identified and characterized <i>Pannier</i> in <i>H. axyridis</i> (<i>HaPnr</i>) and showed it to have two alternative spliced variants named <i>HaPnr-α</i> and <i>HaPnr-β</i>. Analyses of developmental stage expression patterns revealed that <i>HaPnr</i>, <i>HaPnr-α</i> and <i>HaPnr-β</i> were constitutively expressed throughout all developmental stages. To examine the role of <i>HaPnr</i> in <i>H. axyridis</i> development, RNA interference was performed in late ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-31T07:09:12.54Z","creation":"2024-11-12T19:11:57.288Z"},"accession":"S-EPMC9110671","cross_references":{"pubmed":["35592031"],"doi":["10.3389/fphys.2022.909258"]}}