biostudies-literatureUnknown32(5)Rahmati MAmong coronavirus disease 2019 (COVID-19) patients, physically active individuals may be at lower risk of fatal outcomes. However, to date, no meta-analysis has been carried out to investigate the relationship between physical activity (PA) and fatal outcomes in patients with COVID-19. Therefore, this meta-analysis aims to explore the hospitalisation, intensive care unit (ICU) admissions, and mortality rates of COVID-19 patients with a history of PA participation before the onset of the pandemic, and to evaluate the reliability of the evidence. A systematic search of MEDLINE/PubMed, Cumulative Index to Nursing and Allied Health Literature, Scopus, and medRxiv was conducted for articles published up to January 2022. A random-effects meta-analysis was performed to compare disease severity anReviews in medical virologye2349https://www.ebi.ac.uk/biostudies/studies/S-EPMC9111124biostudies-literatureBaseline physical activity is associated with reduced mortality and disease outcomes in COVID-19: A systematic review and meta-analysis.PMC9111124Woo WYon DKShamsi MMShin JIMalakoutinia FLee SWRahmati MSmith LPark SKhoramipour KfalseBaseline physical activity is associated with reduced mortality and disease outcomes in COVID-19: A systematic review and meta-analysis.Among coronavirus disease 2019 (COVID-19) patients, physically active individuals may be at lower risk of fatal outcomes. However, to date, no meta-analysis has been carried out to investigate the relationship between physical activity (PA) and fatal outcomes in patients with COVID-19. Therefore, this meta-analysis aims to explore the hospitalisation, intensive care unit (ICU) admissions, and mortality rates of COVID-19 patients with a history of PA participation before the onset of the pandemic, and to evaluate the reliability of the evidence. A systematic search of MEDLINE/PubMed, Cumulative Index to Nursing and Allied Health Literature, Scopus, and medRxiv was conducted for articles published up to January 2022. A random-effects meta-analysis was performed to compare disease severity an2022-01-01T00:00:00Z2022 Sep2025-04-04T20:37:14.485Z2022-07-20T05:45:44.037ZS-EPMC91111243541635410.1002/rmv.2349