biostudies-literatureUnknown13Lawal OU<h4>Background</h4>Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a leading cause of hospital-associated (HA) and community-associated (CA) infections globally. The multi-drug resistant nature of this pathogen and its capacity to cause outbreaks in hospital and community settings highlight the need for effective interventions, including its surveillance for prevention and control. This study provides an update on the clonal distribution of MRSA in Africa.<h4>Methods</h4>A systematic review was conducted by screening for eligible English, French, and Arabic articles from November 2014 to December 2020, using six electronic databases (PubMed, EBSCOhost, Web of Science, Scopus, African Journals Online, and Google Scholar). Data were retrieved and analyzed according to the PreferFrontiers in microbiology860436https://www.ebi.ac.uk/biostudies/studies/S-EPMC9113548biostudies-literatureA 6-Year Update on the Diversity of Methicillin-Resistant <i>Staphylococcus aureus</i> Clones in Africa: A Systematic Review.PMC9113548Kaba MAbouelfetouh AAbdulgader SMAyobami OMourabit NLawal OUEgyir BShittu AOfalseA 6-Year Update on the Diversity of Methicillin-Resistant <i>Staphylococcus aureus</i> Clones in Africa: A Systematic Review.<h4>Background</h4>Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a leading cause of hospital-associated (HA) and community-associated (CA) infections globally. The multi-drug resistant nature of this pathogen and its capacity to cause outbreaks in hospital and community settings highlight the need for effective interventions, including its surveillance for prevention and control. This study provides an update on the clonal distribution of MRSA in Africa.<h4>Methods</h4>A systematic review was conducted by screening for eligible English, French, and Arabic articles from November 2014 to December 2020, using six electronic databases (PubMed, EBSCOhost, Web of Science, Scopus, African Journals Online, and Google Scholar). Data were retrieved and analyzed according to the Prefer2022-01-01T00:00:00Z20222025-06-01T02:58:34.712Z2024-11-15T18:50:55.156ZS-EPMC91135483559199310.3389/fmicb.2022.860436