{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Xie J"],"pubmed_abstract":["Stem cell therapy is a thriving topic of interest among researchers and clinicians due to evidence of its effectiveness and promising therapeutic advantage in numerous disease conditions as presented by novel biomedical research. However, extensive clinical application of stem cells is limited by its storage and transportation. The emergence of cryopreservation technology has made it possible for living organs, tissues, cells and even living organisms to survive for a long time at deep low temperatures. During the cryopreservation process, stem cell preparations are subject to three major damages: osmotic damage, mechanical damage, and peroxidative damage. Therefore, Assessing the effectiveness and safety of stem cells following cryopreservation is fundamental to the quality control of ste"],"journal":["Frontiers in pharmacology"],"pagination":["907943"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9113563"],"repository":["biostudies-literature"],"pubmed_title":["Principles and Protocols For Post-Cryopreservation Quality Evaluation of Stem Cells in Novel Biomedicine."],"pmcid":["PMC9113563"],"pubmed_authors":["Ekpo MD","Xiao J","Liang Y","Xie J","Zhao G","Tan S","Liu D","Bai X","Zhao H"],"additional_accession":[]},"is_claimable":false,"name":"Principles and Protocols For Post-Cryopreservation Quality Evaluation of Stem Cells in Novel Biomedicine.","description":"Stem cell therapy is a thriving topic of interest among researchers and clinicians due to evidence of its effectiveness and promising therapeutic advantage in numerous disease conditions as presented by novel biomedical research. However, extensive clinical application of stem cells is limited by its storage and transportation. The emergence of cryopreservation technology has made it possible for living organs, tissues, cells and even living organisms to survive for a long time at deep low temperatures. During the cryopreservation process, stem cell preparations are subject to three major damages: osmotic damage, mechanical damage, and peroxidative damage. Therefore, Assessing the effectiveness and safety of stem cells following cryopreservation is fundamental to the quality control of ste","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T21:49:06.493Z","creation":"2025-02-19T03:27:37.128Z"},"accession":"S-EPMC9113563","cross_references":{"pubmed":["35592426"],"doi":["10.3389/fphar.2022.907943"]}}