{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Cardenas CE"],"funding":["NIDCR NIH HHS","NIBIB NIH HHS","NCI NIH HHS"],"pagination":["426-436"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9119288"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["113(2)"],"pubmed_abstract":["<h4>Purpose</h4>Tumor and target volume manual delineation remains a challenging task in head and neck cancer radiation therapy. The purpose of this study was to conduct a multi-institutional evaluation of manual delineations of gross tumor volume (GTV), high-risk clinical target volume (CTV), parotids, and submandibular glands on treatment simulation magnetic resonance scans of patients with oropharyngeal cancer.<h4>Methods and materials</h4>We retrospectively collected pretreatment T1-weighted, T1-weighted with gadolinium contrast, and T2-weighted magnetic resonance imaging scans for 4 patients with oropharyngeal cancer under an institution review board-approved protocol. We provided the scans to 26 radiation oncologists from 7 international cancer centers that participated in this delin"],"journal":["International journal of radiation oncology, biology, physics"],"pubmed_title":["Comprehensive Quantitative Evaluation of Variability in Magnetic Resonance-Guided Delineation of Oropharyngeal Gross Tumor Volumes and High-Risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study."],"pmcid":["PMC9119288"],"funding_grant_id":["R01 CA218148","F31 DE029093","P30 CA016672","P50 CA097007","R01 DE025248","R01 DE028290","R01 CA214825","R25 EB025787","R56 DE025248","R01 CA257814"],"pubmed_authors":["Al-Mamgani AA","Mohamed ASR","Cardenas CE","Terhaard C","Philippens M","Fuller CD","Newbold K","Blinde SE","Kotte A","Raaijmakers C","Karam I","Thomson DJ","Robbins J","Ng SP"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive Quantitative Evaluation of Variability in Magnetic Resonance-Guided Delineation of Oropharyngeal Gross Tumor Volumes and High-Risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study.","description":"<h4>Purpose</h4>Tumor and target volume manual delineation remains a challenging task in head and neck cancer radiation therapy. The purpose of this study was to conduct a multi-institutional evaluation of manual delineations of gross tumor volume (GTV), high-risk clinical target volume (CTV), parotids, and submandibular glands on treatment simulation magnetic resonance scans of patients with oropharyngeal cancer.<h4>Methods and materials</h4>We retrospectively collected pretreatment T1-weighted, T1-weighted with gadolinium contrast, and T2-weighted magnetic resonance imaging scans for 4 patients with oropharyngeal cancer under an institution review board-approved protocol. We provided the scans to 26 radiation oncologists from 7 international cancer centers that participated in this delin","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-26T22:56:22.025Z","creation":"2025-04-06T17:25:41.917Z"},"accession":"S-EPMC9119288","cross_references":{"pubmed":["35124134"],"doi":["10.1016/j.ijrobp.2022.01.050"]}}