{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Po' C"],"pubmed_abstract":["<h4>Background</h4>Moyamoya is a rare progressive cerebral arteriopathy, occurring as an isolated phenomenon (moyamoya disease, MMD) or associated with other conditions (moyamoya syndrome, MMS), responsible for 6-10% of all childhood strokes and transient ischemic attacks (TIAs).<h4>Methods</h4>We conducted a retrospective multicenter study on pediatric-onset MMD/MMS in Italy in order to characterize disease presentation, course, management, neuroradiology, and outcome in a European country.<h4>Results</h4>A total of 65 patients (34/65 women) with MMD (27/65) or MMS (38/65) were included. About 18% (12/65) of patients were asymptomatic and diagnosed incidentally during investigations performed for an underlying condition (incMMS), whereas 82% (53/65) of patients with MMD or MMS were diagno"],"journal":["Frontiers in pediatrics"],"pagination":["892445"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9120837"],"repository":["biostudies-literature"],"pubmed_title":["Pediatric Moyamoya Disease and Syndrome in Italy: A Multicenter Cohort."],"pmcid":["PMC9120837"],"pubmed_authors":["Ragazzi P","Giordano L","Morini G","Scelsa B","Sanfilippo G","Lafe E","Colombatti R","Thyrion FZ","Po' C","Martelli P","Mirone G","Polonara G","Raviglione F","Toni F","Zedde M","Marras CE","Cirillo L","Di Rosa G","Cordelli DM","Nicita F","Cosi A","Sartori S","Foiadelli T","Manara R","Toldo I","Pruna D","Spalice A","Lanterna LA","Sainati L","Baro V","Operto FF","Suppiej A","Carai A","Nosadini M","De Carlo L","Azzolina D","Bova SM","Rollo M","Pascarella R","Cesaroni E","Esposito G","Frigo AC","Grazian L","Savasta S","Campa S","Accorsi P","Iodice A","Cicala D","Greco F","Striano P","Agostini M","Skabar A","Rosati A","Causin F"],"additional_accession":[]},"is_claimable":false,"name":"Pediatric Moyamoya Disease and Syndrome in Italy: A Multicenter Cohort.","description":"<h4>Background</h4>Moyamoya is a rare progressive cerebral arteriopathy, occurring as an isolated phenomenon (moyamoya disease, MMD) or associated with other conditions (moyamoya syndrome, MMS), responsible for 6-10% of all childhood strokes and transient ischemic attacks (TIAs).<h4>Methods</h4>We conducted a retrospective multicenter study on pediatric-onset MMD/MMS in Italy in order to characterize disease presentation, course, management, neuroradiology, and outcome in a European country.<h4>Results</h4>A total of 65 patients (34/65 women) with MMD (27/65) or MMS (38/65) were included. About 18% (12/65) of patients were asymptomatic and diagnosed incidentally during investigations performed for an underlying condition (incMMS), whereas 82% (53/65) of patients with MMD or MMS were diagno","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-05-29T19:23:07.706Z","creation":"2025-05-29T19:23:07.706Z"},"accession":"S-EPMC9120837","cross_references":{"pubmed":["35601411"],"doi":["10.3389/fped.2022.892445"]}}