{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Knitza J"],"funding":["Universitätsklinikum Erlangen","Thermo Fisher Scientific, Freiburg, Germany","Deutsche Forschungsgemeinschaft"],"pagination":["125"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9130452"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24(1)"],"pubmed_abstract":["<h4>Background</h4>Rheumatoid arthritis (RA) requires early diagnosis and tight surveillance of disease activity. Remote self-collection of blood for the analysis of inflammation markers and autoantibodies could improve the monitoring of RA and facilitate the identification of individuals at-risk for RA.<h4>Objective</h4>Randomized, controlled trial to evaluate the accuracy, feasibility, and acceptability of an upper arm self-sampling device (UA) and finger prick-test (FP) to measure capillary blood from RA patients for C-reactive protein (CRP) levels and the presence of IgM rheumatoid factor (RF IgM) and anti-cyclic citrullinated protein antibodies (anti-CCP IgG).<h4>Methods</h4>RA patients were randomly assigned in a 1:1 ratio to self-collection of capillary blood via UA or FP. Venous bl"],"journal":["Arthritis research & therapy"],"pubmed_title":["Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial."],"pmcid":["PMC9130452"],"funding_grant_id":["2886"],"pubmed_authors":["Aubourg T","Matusewicz P","Kleyer A","Bendzuck G","Boeltz S","Hueber AJ","Kronke G","Knitza J","Eimer E","Korinth M","Vuillerme N","Corte G","Elling-Audersch C","Schett G","Simon D","Schuster L","Tascilar K"],"additional_accession":[]},"is_claimable":false,"name":"Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial.","description":"<h4>Background</h4>Rheumatoid arthritis (RA) requires early diagnosis and tight surveillance of disease activity. Remote self-collection of blood for the analysis of inflammation markers and autoantibodies could improve the monitoring of RA and facilitate the identification of individuals at-risk for RA.<h4>Objective</h4>Randomized, controlled trial to evaluate the accuracy, feasibility, and acceptability of an upper arm self-sampling device (UA) and finger prick-test (FP) to measure capillary blood from RA patients for C-reactive protein (CRP) levels and the presence of IgM rheumatoid factor (RF IgM) and anti-cyclic citrullinated protein antibodies (anti-CCP IgG).<h4>Methods</h4>RA patients were randomly assigned in a 1:1 ratio to self-collection of capillary blood via UA or FP. Venous bl","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2026-06-04T07:59:09.449Z","creation":"2024-11-11T23:02:04.85Z"},"accession":"S-EPMC9130452","cross_references":{"pubmed":["35614488"],"doi":["10.1186/s13075-022-02809-7"]}}