{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Guo J"],"pubmed_abstract":["<h4>Background</h4>Epidemiological evidence on the relationship between benign ovarian tumors and ovarian cancer risk has been controversial; therefore, this systematic review and meta-analysis evaluated this association.<h4>Methods</h4>The PubMed and Web of Knowledge databases were searched for eligible studies published up to April 30, 2020. The study-specific risk estimates were pooled using a random-effects model.<h4>Results</h4>Ten articles (two cohorts, seven case-control studies, and one pooled analysis of eight case-control studies) with 10331 ovarian cancer patients were included. Benign ovarian tumors were associated with an increased risk of ovarian cancer (pooled relative risk [RR]=1.39, 95% confidence interval [CI]: 1.01-1.90), with high heterogeneity among studies. The pooled"],"journal":["Frontiers in oncology"],"pagination":["895618"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9133501"],"repository":["biostudies-literature"],"pubmed_title":["Association Between Benign Ovarian Tumors and Ovarian Cancer Risk: A Meta-Analysis of Ten Epidemiological Studies."],"pmcid":["PMC9133501"],"pubmed_authors":["Guo J","Gu X","Feng H"],"additional_accession":[]},"is_claimable":false,"name":"Association Between Benign Ovarian Tumors and Ovarian Cancer Risk: A Meta-Analysis of Ten Epidemiological Studies.","description":"<h4>Background</h4>Epidemiological evidence on the relationship between benign ovarian tumors and ovarian cancer risk has been controversial; therefore, this systematic review and meta-analysis evaluated this association.<h4>Methods</h4>The PubMed and Web of Knowledge databases were searched for eligible studies published up to April 30, 2020. The study-specific risk estimates were pooled using a random-effects model.<h4>Results</h4>Ten articles (two cohorts, seven case-control studies, and one pooled analysis of eight case-control studies) with 10331 ovarian cancer patients were included. Benign ovarian tumors were associated with an increased risk of ovarian cancer (pooled relative risk [RR]=1.39, 95% confidence interval [CI]: 1.01-1.90), with high heterogeneity among studies. The pooled","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T11:29:19.192Z","creation":"2025-04-04T11:29:19.192Z"},"accession":"S-EPMC9133501","cross_references":{"pubmed":["35646702"],"doi":["10.3389/fonc.2022.895618"]}}