{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang KC"],"funding":["CIHR"],"pagination":["101283"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9133752"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["3(2)"],"pubmed_abstract":["RNA-sequencing and quantitative proteomic profiling simultaneously measure thousands of molecules and provide opportunities to decipher the transcriptomic and proteomic landscapes of cohort specimens for basic and health research. We present a protocol for the analysis of paired transcriptome and proteome data to identify and compare molecular subgroups among cohort specimens. We demonstrate a streamlined analysis workflow, applicable for both transcriptome and proteome data, which allows the comparison of two data types for RNA-protein variations and for derivation of biological implications. For complete details on the use and execution of this protocol, please refer to Yang et al. (2021)."],"journal":["STAR protocols"],"pubmed_title":["Protocol for analysis of RNA-sequencing and proteome profiling data for subgroup identification and comparison."],"pmcid":["PMC9133752"],"funding_grant_id":["PJT-159536"],"pubmed_authors":["Gorski SM","Yang KC"],"additional_accession":[]},"is_claimable":false,"name":"Protocol for analysis of RNA-sequencing and proteome profiling data for subgroup identification and comparison.","description":"RNA-sequencing and quantitative proteomic profiling simultaneously measure thousands of molecules and provide opportunities to decipher the transcriptomic and proteomic landscapes of cohort specimens for basic and health research. We present a protocol for the analysis of paired transcriptome and proteome data to identify and compare molecular subgroups among cohort specimens. We demonstrate a streamlined analysis workflow, applicable for both transcriptome and proteome data, which allows the comparison of two data types for RNA-protein variations and for derivation of biological implications. For complete details on the use and execution of this protocol, please refer to Yang et al. (2021).","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-04T13:29:39.725Z","creation":"2024-11-13T05:15:57.515Z"},"accession":"S-EPMC9133752","cross_references":{"pubmed":["35634361"],"doi":["10.1016/j.xpro.2022.101283"]}}