biostudies-literatureUnknown146(5)Gradel KOCommunity-acquired bacteraemia patients (n = 2472), Denmark, 2000-2008. Albumin, C-reactive protein (CRP) and haemoglobin (Hb) measured 2000-2010. We assessed daily mean levels of albumin, CRP and Hb from 30 days before to 30 days after bacteraemia and correlations between albumin vs. CRP and albumin vs. Hb. In linear regression models, we evaluated the contribution of CRP, Hb, chronic and acute variables to the albumin level variations. The mean albumin level (33.6 g/l) was steady before day 1, declined to 29.3 g/l on day 1 with little increase afterward. The mean CRP increased from day -5, peaked on day 1 and declined thereafter. The mean Hb level was fairly constant during days -30/30. Albumin was inversely (R range, - 0.18/-0.47, P < 10-4) correlated with the CRP level and positively (Epidemiology and infection648-655https://www.ebi.ac.uk/biostudies/studies/S-EPMC9134564biostudies-literatureHypoalbuminaemia as a marker of trans-capillary leakage in community-acquired bacteraemia patients.PMC9134564Jensen TGVinholt PJMagnussen BKolmos HJPedersen CLassen ATGradel KOfalseHypoalbuminaemia as a marker of trans-capillary leakage in community-acquired bacteraemia patients.Community-acquired bacteraemia patients (n = 2472), Denmark, 2000-2008. Albumin, C-reactive protein (CRP) and haemoglobin (Hb) measured 2000-2010. We assessed daily mean levels of albumin, CRP and Hb from 30 days before to 30 days after bacteraemia and correlations between albumin vs. CRP and albumin vs. Hb. In linear regression models, we evaluated the contribution of CRP, Hb, chronic and acute variables to the albumin level variations. The mean albumin level (33.6 g/l) was steady before day 1, declined to 29.3 g/l on day 1 with little increase afterward. The mean CRP increased from day -5, peaked on day 1 and declined thereafter. The mean Hb level was fairly constant during days -30/30. Albumin was inversely (R range, - 0.18/-0.47, P < 10-4) correlated with the CRP level and positively (2018-01-01T00:00:00Z2018 Apr2025-04-05T15:06:55.513Z2025-04-05T15:06:55.513ZS-EPMC91345642945757610.1017/S095026881800027410.1017/s0950268818000274