{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Angelucci CB"],"funding":["Italian Ministry of Health"],"pagination":["1304"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9137499"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(10)"],"pubmed_abstract":["<i>Brucella ceti</i>, a zoonotic pathogen of major concern to cetacean health and conservation, is responsible for severe meningo-encephalitic/myelitic lesions in striped dolphins (<i>Stenella coeruleoalba</i>), often leading to their stranding and death. This study investigated, for the first time, the cellular prion protein (PrP<sup>c</sup>) expression in the brain tissue from <i>B. ceti</i>-infected, neurobrucellosis-affected striped dolphins. Seven <i>B. ceti</i>-infected, neurobrucellosis-affected striped dolphins, found stranded along the Italian coastline (6) and in the Canary Islands (1), were investigated, along with five <i>B. ceti</i>-uninfected striped dolphins from the coast of Italy, carrying no brain lesions, which served as negative controls. Western Blot (WB) and immunohis"],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Cellular Prion Protein Expression in the Brain Tissue from <i>Brucella ceti</i>-Infected Striped Dolphins (<i>Stenella coeruleoalba</i>)."],"pmcid":["PMC9137499"],"funding_grant_id":["IZSAM 03/16/RC."],"pubmed_authors":["Tittarelli M","Giacominelli-Stuffler R","Baffoni M","Di Francesco CE","Fernandez A","Grattarola C","Petrella A","Sierra E","Di Guardo G","Di Renzo L","Angelucci CB","Di Francesco G","Mazzariol S"],"additional_accession":[]},"is_claimable":false,"name":"Cellular Prion Protein Expression in the Brain Tissue from <i>Brucella ceti</i>-Infected Striped Dolphins (<i>Stenella coeruleoalba</i>).","description":"<i>Brucella ceti</i>, a zoonotic pathogen of major concern to cetacean health and conservation, is responsible for severe meningo-encephalitic/myelitic lesions in striped dolphins (<i>Stenella coeruleoalba</i>), often leading to their stranding and death. This study investigated, for the first time, the cellular prion protein (PrP<sup>c</sup>) expression in the brain tissue from <i>B. ceti</i>-infected, neurobrucellosis-affected striped dolphins. Seven <i>B. ceti</i>-infected, neurobrucellosis-affected striped dolphins, found stranded along the Italian coastline (6) and in the Canary Islands (1), were investigated, along with five <i>B. ceti</i>-uninfected striped dolphins from the coast of Italy, carrying no brain lesions, which served as negative controls. Western Blot (WB) and immunohis","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-04T10:42:30.279Z","creation":"2025-04-04T10:42:30.279Z"},"accession":"S-EPMC9137499","cross_references":{"pubmed":["35625150"],"doi":["10.3390/ani12101304"]}}