biostudies-literatureUnknown11(5)Ayariga JA<i>Salmonella typhimurium</i> (<i>S. typhimurium</i>) is one of the major food and waterborne bacteria that causes several health outbreaks in the world. Although there are few antibiotics against this bacterium, some of these drugs are challenged with resistance and toxicity. To mitigate this challenge, our group explored the ethnomedicinal/herbalism knowledge about a certain spice used in Northern Ghana in West Africa against bacterial and viral infection. This plant is <i>Capsicum chinense</i> (<i>C. chinense</i>). The plant is one of the commonest food spices consumed across the world. The seed of the plant contains both capsaicin and dihydrocapsaicin. Apart from capsaicin and dihydrocapsaicin, other major capsaicinoids in <i>C. chinense</i> include nordihydrocapsaicin, homodihydrocapsAntibiotics (Basel, Switzerland)666https://www.ebi.ac.uk/biostudies/studies/S-EPMC9137802biostudies-literatureCapsaicin Potently Blocks <i>Salmonella typhimurium</i> Invasion of Vero Cells.PMC9137802Amrutha BVillafane RAbugri DAAyariga JAfalseCapsaicin Potently Blocks <i>Salmonella typhimurium</i> Invasion of Vero Cells.<i>Salmonella typhimurium</i> (<i>S. typhimurium</i>) is one of the major food and waterborne bacteria that causes several health outbreaks in the world. Although there are few antibiotics against this bacterium, some of these drugs are challenged with resistance and toxicity. To mitigate this challenge, our group explored the ethnomedicinal/herbalism knowledge about a certain spice used in Northern Ghana in West Africa against bacterial and viral infection. This plant is <i>Capsicum chinense</i> (<i>C. chinense</i>). The plant is one of the commonest food spices consumed across the world. The seed of the plant contains both capsaicin and dihydrocapsaicin. Apart from capsaicin and dihydrocapsaicin, other major capsaicinoids in <i>C. chinense</i> include nordihydrocapsaicin, homodihydrocaps2022-01-01T00:00:00Z2022 May2025-04-18T20:35:35.65Z2025-04-07T08:29:15.845ZS-EPMC91378023562531010.3390/antibiotics11050666