biostudies-literatureBaeza JATemasek Foundation under the Singapore Millennium Foundation Research Grant Programme903https://www.ebi.ac.uk/biostudies/studies/S-EPMC9140397biostudies-literatureUnknown13(5)The boring giant clam <i>Tridacna crocea</i> is an evolutionary, ecologically, economically, and culturally important reef-dwelling bivalve targeted by a profitable ornamental fishery in the Indo-Pacific Ocean. In this study, we developed genomic resources for <i>T. crocea</i>. Using low-pass (=low-coverage, ~6×) short read sequencing, this study, for the first time, estimated the genome size, unique genome content, and nuclear repetitive elements, including the 45S rRNA DNA operon, in <i>T. crocea</i>. Furthermore, we tested if the mitochondrial genome can be assembled from RNA sequencing data. The haploid genome size estimated using a k-mer strategy was 1.31-1.39 Gbp, which is well within the range reported before for other members of the family Cardiidae. Unique genome content estimatesGenesGenomic Survey and Resources for the Boring Giant Clam <i>Tridacna crocea</i>.PMC9140397A-0003203-01-00Huang DNeo MLBaeza JAfalseGenomic Survey and Resources for the Boring Giant Clam <i>Tridacna crocea</i>.The boring giant clam <i>Tridacna crocea</i> is an evolutionary, ecologically, economically, and culturally important reef-dwelling bivalve targeted by a profitable ornamental fishery in the Indo-Pacific Ocean. In this study, we developed genomic resources for <i>T. crocea</i>. Using low-pass (=low-coverage, ~6×) short read sequencing, this study, for the first time, estimated the genome size, unique genome content, and nuclear repetitive elements, including the 45S rRNA DNA operon, in <i>T. crocea</i>. Furthermore, we tested if the mitochondrial genome can be assembled from RNA sequencing data. The haploid genome size estimated using a k-mer strategy was 1.31-1.39 Gbp, which is well within the range reported before for other members of the family Cardiidae. Unique genome content estimates2022-01-01T00:00:00Z2022 May2026-04-08T10:13:26.324Z2025-04-04T13:30:22.361ZS-EPMC91403973562728810.3390/genes13050903