{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(5)"],"submitter":["Liao J"],"pubmed_abstract":["Circular RNA (CircRNA) is related to tumor development. Nevertheless, the regulation and function of hsa_circ_0006692 and its interactions with miR-205-5p and <i>CDK19</i> in the development of non-small-cell lung cancer (NSCLC) were un-explored. The correlations of expression levels of hsa_circ_0006692 in NSCLC specimens and cells with pathological characteristics were studied. The interactions of hsa_circ_0006692 with miR-205-5p and <i>CDK19</i> were assessed with real-time PCR, RNA-binding protein immunoprecipitation (RIP), luciferase reporter, RNA pull-down, and fluorescence in situ hybridization (FISH). The roles of hsa_circ_0006692 on cell growth, invasion, and migration in vitro and metastasis in vivo were evaluated. Hsa_circ_0006692 was over-expressed in 60 cases of NSCLC specimens"],"journal":["Genes"],"pagination":["846"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9141027"],"repository":["biostudies-literature"],"pubmed_title":["Hsa_circ_0006692 Promotes Lung Cancer Progression via miR-205-5p/CDK19 Axis."],"pmcid":["PMC9141027"],"pubmed_authors":["Liao J","Huang T","Chen Z","Lin G","Lin X","Zheng Q","Luo X","Zhang L","Su Y","Xu H","Lin K"],"additional_accession":[]},"is_claimable":false,"name":"Hsa_circ_0006692 Promotes Lung Cancer Progression via miR-205-5p/CDK19 Axis.","description":"Circular RNA (CircRNA) is related to tumor development. Nevertheless, the regulation and function of hsa_circ_0006692 and its interactions with miR-205-5p and <i>CDK19</i> in the development of non-small-cell lung cancer (NSCLC) were un-explored. The correlations of expression levels of hsa_circ_0006692 in NSCLC specimens and cells with pathological characteristics were studied. The interactions of hsa_circ_0006692 with miR-205-5p and <i>CDK19</i> were assessed with real-time PCR, RNA-binding protein immunoprecipitation (RIP), luciferase reporter, RNA pull-down, and fluorescence in situ hybridization (FISH). The roles of hsa_circ_0006692 on cell growth, invasion, and migration in vitro and metastasis in vivo were evaluated. Hsa_circ_0006692 was over-expressed in 60 cases of NSCLC specimens","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-19T17:39:09.219Z","creation":"2025-02-19T04:30:48.512Z"},"accession":"S-EPMC9141027","cross_references":{"pubmed":["35627232"],"doi":["10.3390/genes13050846"]}}