{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(5)"],"submitter":["Buonaurio F"],"pubmed_abstract":["<h4>Background</h4>The objective of this study is to evaluate the effects of traffic on human health comparing biomonitoring data measured during the COVID-19 lockdown, when restrictions led to a 40% reduction in airborne benzene in Rome and a 36% reduction in road traffic, to the same parameters measured in 2021.<h4>Methods</h4>Biomonitoring was performed on 49 volunteers, determining the urinary metabolites of the most abundant traffic pollutants, such as benzene and PAHs, and oxidative stress biomarkers by HPLC/MS-MS, 28 elements by ICP/MS and metabolic phenotypes by NMR.<h4>Results</h4>Means of s-phenylmercaputric acid (SPMA), metabolites of naphthalene and nitropyrene in 2020 are 20% lower than in 2021, while 1-OH-pyrene was 30% lower. A reduction of 40% for 8-oxo-7,8-dihydroguanosine"],"journal":["Toxics"],"pagination":["267"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9143243"],"repository":["biostudies-literature"],"pubmed_title":["Biomonitoring of Exposure to Urban Pollutants and Oxidative Stress during the COVID-19 Lockdown in Rome Residents."],"pmcid":["PMC9143243"],"pubmed_authors":["Pigini D","Paci E","Astolfi ML","Giampaoli O","Spagnoli M","Ancona C","Tranfo G","Buonaurio F","Sciubba F","Miccheli A","Canepari S","Borra F"],"additional_accession":[]},"is_claimable":false,"name":"Biomonitoring of Exposure to Urban Pollutants and Oxidative Stress during the COVID-19 Lockdown in Rome Residents.","description":"<h4>Background</h4>The objective of this study is to evaluate the effects of traffic on human health comparing biomonitoring data measured during the COVID-19 lockdown, when restrictions led to a 40% reduction in airborne benzene in Rome and a 36% reduction in road traffic, to the same parameters measured in 2021.<h4>Methods</h4>Biomonitoring was performed on 49 volunteers, determining the urinary metabolites of the most abundant traffic pollutants, such as benzene and PAHs, and oxidative stress biomarkers by HPLC/MS-MS, 28 elements by ICP/MS and metabolic phenotypes by NMR.<h4>Results</h4>Means of s-phenylmercaputric acid (SPMA), metabolites of naphthalene and nitropyrene in 2020 are 20% lower than in 2021, while 1-OH-pyrene was 30% lower. A reduction of 40% for 8-oxo-7,8-dihydroguanosine","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-27T04:49:27.747Z","creation":"2024-11-06T15:42:46.178Z"},"accession":"S-EPMC9143243","cross_references":{"pubmed":["35622680"],"doi":["10.3390/toxics10050267"]}}