{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lv Z"],"funding":["National Key Research and Development Program of China"],"pagination":["971"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9146948"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(5)"],"pubmed_abstract":["This study mainly evaluated the broad-spectrum fungicidal activity of ε-poly L lysine (ε-PL) against 12 pathogenic fungi. We further demonstrated synergistic antifungal activity of ε-PL combined with wuyiencin against <i>Botryris cinerea</i>. The combined bio-fungicide achieved an inhibition rate of 100% for mycelial growth using ε-PL at 500 μg/mL + wuyiencin at 50 μg/mL and for spore germination using ε-PL at 200 μg/mL + wuyiencin at 80 μg/mL in vitro. This synergistic spore and mycelia-damaging effect of the combination was confirmed using scanning electron microscopy. In vivo assays with combined bio-fungicide (1500 μg/mL ε-PL + 60 μg/mL wuyiencin) on detached leaves showed depressed growth and development of the spores of <i>B. cinerea</i>. The synergistic effect was further tested in "],"journal":["Microorganisms"],"pubmed_title":["Effects of ε-Poly-L-Lysine Combined with Wuyiencin as a Bio-Fungicide against <i>Botryris cinerea</i>."],"pmcid":["PMC9146948"],"funding_grant_id":["No. 2019YFD1002000"],"pubmed_authors":["Lv Z","Ge B","Shi L","Zhang K","Lu Y","Li B"],"additional_accession":[]},"is_claimable":false,"name":"Effects of ε-Poly-L-Lysine Combined with Wuyiencin as a Bio-Fungicide against <i>Botryris cinerea</i>.","description":"This study mainly evaluated the broad-spectrum fungicidal activity of ε-poly L lysine (ε-PL) against 12 pathogenic fungi. We further demonstrated synergistic antifungal activity of ε-PL combined with wuyiencin against <i>Botryris cinerea</i>. The combined bio-fungicide achieved an inhibition rate of 100% for mycelial growth using ε-PL at 500 μg/mL + wuyiencin at 50 μg/mL and for spore germination using ε-PL at 200 μg/mL + wuyiencin at 80 μg/mL in vitro. This synergistic spore and mycelia-damaging effect of the combination was confirmed using scanning electron microscopy. In vivo assays with combined bio-fungicide (1500 μg/mL ε-PL + 60 μg/mL wuyiencin) on detached leaves showed depressed growth and development of the spores of <i>B. cinerea</i>. The synergistic effect was further tested in ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-04-22T18:23:11.248Z","creation":"2025-04-06T02:24:32.945Z"},"accession":"S-EPMC9146948","cross_references":{"pubmed":["35630418"],"doi":["10.3390/microorganisms10050971"]}}