biostudies-literatureScurria AMinistry of Education, Universities and Research3243https://www.ebi.ac.uk/biostudies/studies/S-EPMC9147265biostudies-literatureUnknown27(10)DRIFT, HPLC-MS, and SPME-GC/MS analyses were used to unveil the structure and the main functional compounds of red (blood) orange (<i>Citrus sinensis</i>) and bitter orange (<i>Citrus aurantium</i>). The IntegroPectin samples show evidence that these new citrus pectins are comprised of pectin rich in RG-I hairy regions functionalized with citrus biophenols, chiefly flavonoids and volatile molecules, mostly terpenes. Remarkably, IntegroPectin from the peel of fresh bitter oranges is the first high methoxyl citrus pectin extracted via hydrodynamic cavitation, whereas the red orange IntegroPectin is a low methoxyl pectin. <i>C. aurantium</i> IntegroPectin has a uniquely high concentration of adsorbed flavonoids, especially the flavanone glycosides hesperidin, naringin, and eriocitrin.Molecules (Basel, Switzerland)Red Orange and Bitter Orange IntegroPectin: Structure and Main Functional Compounds.PMC9147265D.M. 1061/2021 Ph.D. programmeAlbanese LMeneguzzo FScurria AGarcia ARIlharco LMSciortino MPagliaro MFidalgo AAvellone GCiriminna RfalseRed Orange and Bitter Orange IntegroPectin: Structure and Main Functional Compounds.DRIFT, HPLC-MS, and SPME-GC/MS analyses were used to unveil the structure and the main functional compounds of red (blood) orange (<i>Citrus sinensis</i>) and bitter orange (<i>Citrus aurantium</i>). The IntegroPectin samples show evidence that these new citrus pectins are comprised of pectin rich in RG-I hairy regions functionalized with citrus biophenols, chiefly flavonoids and volatile molecules, mostly terpenes. Remarkably, IntegroPectin from the peel of fresh bitter oranges is the first high methoxyl citrus pectin extracted via hydrodynamic cavitation, whereas the red orange IntegroPectin is a low methoxyl pectin. <i>C. aurantium</i> IntegroPectin has a uniquely high concentration of adsorbed flavonoids, especially the flavanone glycosides hesperidin, naringin, and eriocitrin.2022-01-01T00:00:00Z2022 May2025-04-05T11:58:24.501Z2025-04-05T11:58:24.501ZS-EPMC91472653563072010.3390/molecules27103243