{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(2)"],"submitter":["Schmutzler RK"],"pubmed_abstract":["<h4>Background</h4>Risk-adjusted cancer screening and prevention is a promising and continuously emerging option for improving cancer prevention. It is driven by increasing knowledge of risk factors and the ability to determine them for individual risk prediction. However, there is a knowledge gap between evidence of increased risk and evidence of the effectiveness and efficiency of clinical preventive interventions based on increased risk. This gap is, in particular, aggravated by the extensive availability of genetic risk factor diagnostics, since the question of appropriate preventive measures immediately arises when an increased risk is identified. However, collecting proof of effective preventive measures, ideally by prospective randomized preventive studies, typically requires very l"],"journal":["Breast care (Basel, Switzerland)"],"pagination":["208-223"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9149472"],"repository":["biostudies-literature"],"pubmed_title":["Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors."],"pmcid":["PMC9149472"],"pubmed_authors":["Rhiem K","Kast K","Houwaart S","Emons G","Dabrock P","Spranger T","Gronwald J","Devilee P","Moorthie S","Borisch B","Boccia S","Hall P","Eccles D","Huster S","Schmutzler RK","Linn SC","Pharoah P","Woopen C","Stoppa-Lyonnet D","Balmana J","Katalinic A","Schmitz-Luhn B","van Delden JJM","van den Bulcke M","Gaissmaier W"],"additional_accession":[]},"is_claimable":false,"name":"Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.","description":"<h4>Background</h4>Risk-adjusted cancer screening and prevention is a promising and continuously emerging option for improving cancer prevention. It is driven by increasing knowledge of risk factors and the ability to determine them for individual risk prediction. However, there is a knowledge gap between evidence of increased risk and evidence of the effectiveness and efficiency of clinical preventive interventions based on increased risk. This gap is, in particular, aggravated by the extensive availability of genetic risk factor diagnostics, since the question of appropriate preventive measures immediately arises when an increased risk is identified. However, collecting proof of effective preventive measures, ideally by prospective randomized preventive studies, typically requires very l","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Apr","modification":"2026-03-17T15:55:11.503Z","creation":"2025-04-19T13:16:21.393Z"},"accession":"S-EPMC9149472","cross_references":{"pubmed":["35702492"],"doi":["10.1159/000517182"]}}