biostudies-literaturePerez-Merino EMJunta de Extremadura957-965https://www.ebi.ac.uk/biostudies/studies/S-EPMC9151464biostudies-literatureUnknown36(3)<h4>Background</h4>It has not been determined whether ileal appearance differs among dogs with chronic inflammatory enteropathy (CIE) and different serum concentrations of cobalamin.<h4>Objective</h4>To compare endoscopic and histologic ileal findings in dogs with CIE and different serum cobalamin concentrations and then evaluate the correlation of ileal changes to cobalamin serum concentration using updated scoring systems to assess the ileum.<h4>Animals</h4>Sixty-eight dogs with CIE.<h4>Methods</h4>Retrospective study. Frequency of ileal features and ileal histologic and endoscopic scores (IHS and IES) were obtained and compared among CIE dogs with severe hypocobalaminemia (SHC; <200 ng/L), hypocobalaminemia (HC; 200-350 ng/L), or normocobalaminemia (NC; >350 ng/L). The correlation of IHJournal of veterinary internal medicineRelationship between serum cobalamin concentration and endoscopic ileal appearance and histology in dogs with chronic inflammatory enteropathy.PMC9151464GR21085Duque-Carrasco FJPastor-Sirvent NPerez-Merino EMCristobal-Verdejo IUson-Casaus JMEspadas-Gonzalez LfalseRelationship between serum cobalamin concentration and endoscopic ileal appearance and histology in dogs with chronic inflammatory enteropathy.<h4>Background</h4>It has not been determined whether ileal appearance differs among dogs with chronic inflammatory enteropathy (CIE) and different serum concentrations of cobalamin.<h4>Objective</h4>To compare endoscopic and histologic ileal findings in dogs with CIE and different serum cobalamin concentrations and then evaluate the correlation of ileal changes to cobalamin serum concentration using updated scoring systems to assess the ileum.<h4>Animals</h4>Sixty-eight dogs with CIE.<h4>Methods</h4>Retrospective study. Frequency of ileal features and ileal histologic and endoscopic scores (IHS and IES) were obtained and compared among CIE dogs with severe hypocobalaminemia (SHC; <200 ng/L), hypocobalaminemia (HC; 200-350 ng/L), or normocobalaminemia (NC; >350 ng/L). The correlation of IH2022-01-01T00:00:00Z2022 May2026-07-14T16:46:27.526Z2025-04-19T17:47:59.019ZS-EPMC91514643547552510.1111/jvim.16436