{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["52(6)"],"submitter":["Cha JJ"],"pubmed_abstract":["<h4>Background and objectives</h4>Endovascular therapy (EVT) first strategy has been widely adopted for the treatment of chronic limb threatening ischemia (CLTI) patients in real-world practice. This study aimed to investigate long-term outcomes of CLTI patients who underwent EVT and identify prognostic factors.<h4>Methods</h4>From the retrospective cohorts of a Korean multicenter endovascular therapy registry, 1,036 patients with CLTI (792 men, 68.8 ± 9.5 years) were included. The primary endpoint was amputation-free survival (AFS) defined as the absence of major amputation or death. Secondary endpoints were major adverse limb events (MALE; a composite of major amputation, minor amputation, and reintervention).<h4>Results</h4>Five-year AFS and freedom from MALE were 69.8% and 61%, respect"],"journal":["Korean circulation journal"],"pagination":["429-440"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9160641"],"repository":["biostudies-literature"],"pubmed_title":["Long-term Clinical Outcomes and Prognostic Factors After Endovascular Treatment in Patients With Chronic Limb Threatening Ischemia."],"pmcid":["PMC9160641"],"pubmed_authors":["Choi D","Yu CW","Kim H","K-VIS (Korean Vascular Intervention Society) investigators","Chae IH","Koh YS","Yoon CH","Choi SH","Kim JY","Lee SW","Min PK","Ko YG","Lee SR","Cha JJ","Lee JH"],"additional_accession":[]},"is_claimable":false,"name":"Long-term Clinical Outcomes and Prognostic Factors After Endovascular Treatment in Patients With Chronic Limb Threatening Ischemia.","description":"<h4>Background and objectives</h4>Endovascular therapy (EVT) first strategy has been widely adopted for the treatment of chronic limb threatening ischemia (CLTI) patients in real-world practice. This study aimed to investigate long-term outcomes of CLTI patients who underwent EVT and identify prognostic factors.<h4>Methods</h4>From the retrospective cohorts of a Korean multicenter endovascular therapy registry, 1,036 patients with CLTI (792 men, 68.8 ± 9.5 years) were included. The primary endpoint was amputation-free survival (AFS) defined as the absence of major amputation or death. Secondary endpoints were major adverse limb events (MALE; a composite of major amputation, minor amputation, and reintervention).<h4>Results</h4>Five-year AFS and freedom from MALE were 69.8% and 61%, respect","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2026-04-08T11:09:28.082Z","creation":"2025-02-19T02:44:07.279Z"},"accession":"S-EPMC9160641","cross_references":{"pubmed":["35257522"],"doi":["10.4070/kcj.2021.0342"]}}