biostudies-literatureLin HShanghai Science and Technology FoundationDeutsche ForschungsgemeinschaftNational Natural Science Foundation of China95https://www.ebi.ac.uk/biostudies/studies/S-EPMC9166923biostudies-literatureUnknown13(1)<h4>Background</h4>Estimating liver function reserve is essential for preoperative surgical planning and predicting post-hepatectomy complications in patients with hepatocellular carcinoma (HCC). We investigated hepatic viscoelasticity quantified by tomoelastography, a multifrequency magnetic resonance elastography technique, to predict liver function reserve.<h4>Methods</h4>One hundred fifty-six patients with suspected HCC (mean age, 60 ± 1 years; 131 men) underwent preoperative tomoelastography examination between July 2020 and August 2021. Sixty-nine were included in the final analysis, and their 15-min indocyanine green retention rates (ICG-R15s) were obtained to determine liver function reserve. Tomoelastography quantified the shear wave speed (c, m/s), which represents stiffness, andInsights into imagingTomoelastography based on multifrequency MR elastography predicts liver function reserve in patients with hepatocellular carcinoma: a prospective study.PMC916692321TS140060081901694SFB1340 Matrix-In-VisionBIOQIC GRK 2260Yang YGuo JSack ILin HChen YLi RWang YXu XMa DYang CZhou JYan FfalseTomoelastography based on multifrequency MR elastography predicts liver function reserve in patients with hepatocellular carcinoma: a prospective study.<h4>Background</h4>Estimating liver function reserve is essential for preoperative surgical planning and predicting post-hepatectomy complications in patients with hepatocellular carcinoma (HCC). We investigated hepatic viscoelasticity quantified by tomoelastography, a multifrequency magnetic resonance elastography technique, to predict liver function reserve.<h4>Methods</h4>One hundred fifty-six patients with suspected HCC (mean age, 60 ± 1 years; 131 men) underwent preoperative tomoelastography examination between July 2020 and August 2021. Sixty-nine were included in the final analysis, and their 15-min indocyanine green retention rates (ICG-R15s) were obtained to determine liver function reserve. Tomoelastography quantified the shear wave speed (c, m/s), which represents stiffness, and2022-01-01T00:00:00Z2022 Jun2025-04-05T11:53:12.655Z2025-02-19T04:57:31.312ZS-EPMC91669233565753410.1186/s13244-022-01232-5