biostudies-literatureUnknown23(1)Del Cura-Gonzalez I<h4>Background</h4>The progressive ageing of the population is leading to an increase in multimorbidity and polypharmacy, which in turn may increase the risk of hospitalization and mortality. The enhancement of care with information and communications technology (ICT) can facilitate the use of prescription evaluation tools and support system for decision-making (DSS) with the potential of optimizing the healthcare delivery process.<h4>Objective</h4>To assess the effectiveness and cost-effectiveness of the complex intervention MULTIPAP Plus, compared to usual care, in improving prescriptions for young-old patients (65-74 years old) with multimorbidity and polypharmacy in primary care.<h4>Methods/design</h4>This is a pragmatic cluster-randomized clinical trial with a follow-up of 18 months iTrials479https://www.ebi.ac.uk/biostudies/studies/S-EPMC9178530biostudies-literatureEffectiveness of the MULTIPAP Plus intervention in youngest-old patients with multimorbidity and polypharmacy aimed at improving prescribing practices in primary care: study protocol of a cluster randomized trial.PMC9178530Del-Olmo-Ribagorda MIPoncel-Falco AAzcoaga-Lorenzo AIbarrondo-Fernandez-Ladreda ISegura-Dominguez NLacasa-Serrano MECarretero-Ramos RGarcia-Agua-Soler NLasheras-Barrio MGarcia-De-Blas FCarmona-Pirez JSantos-Munoz DPolentinos-Castro EMiguel-Abanto MLALopez-Serrano BRedondo-de-Pedro SCaceres-Cortes MCVinuela-Beneitez MEBliek-Bueno KFidalgo-Baz MJMartinez-Sarmiento AILozano-Hernandez CTorrubia-Fernandez MJLopez-Alonso BGarcia-Carrera ANarbona-Carrion GFGarcia-Gutierrez-Munoz CBandres-Liso ACSanchez-Jordan RVarela-Varela CQuesada-Fernandez TGarcia-Ruiz TAza-Pascual-Salcedo MGimeno-Feliu LAFernandez-Fernandez YCortes-Pellicer JMAguilar-Heredia YGonzalez-Garcia CFPastor-Estebanez MDominguez-Santaella MRodriguez-Barrientos REwa-Barnas TBujalance-Zafra MJMuros-Munoz CMMartinez-Sanchez RMaza-Invernon ACGarces-Ranz JDMULTIPAP PLUS GroupMartin-Aurioles ELorenzo-Borda MDel Cura-Gonzalez ICharte-Alegre MEMartin-Fernandez JNavarro-Jimenez JMAlcantarilla-Reyes EMLopez-Rodriguez JACano-Del-Pozo MFernandez-Giron MSan-Miguel-Marinero MTde Cienfuegos Hernandez MAEstrada-Leon AHIoakeim-Skoufa IFernandez-Sanchez JCGonzalez-Vega MJDelgado-Marroquin MTGomez-Suarez ENavarro-Gallego MIPelaez-Laguno CBarcelo-Garach EAbadia-Taira MBGimenez-Baratech ACOrtigosa-Arrabal MPAra-Bardaji PVazquez-Alarcon RLTejero-Garcia ISaiz-Ladera GMGarcia-Arpa NRodriguez-Fabre MJSosa-Alonso AAlcaraz-Borrajo MCarrillo-Soria SDAbad-Esteban AMEscobar-Gallegos MDMMarquez-Chamizo MIMorso-Pelaez MPAlvarez-Villalba MGarcia-Lozano MJCastillo-Jimenez MGarcia-Garcia-Alcaniz MDPCarbonero-Martin AIClerencia-Sierra MMora-Garcia ELopez-Fernandez GRico-Blazquez MMarengoni ADel Pilar Barnestein-Fonseca MMarta-Moreno JFerrer-Zapata INavarro-Martin JARioja-Delgado EMGomez-Ciriano JIFons-Canizares SOlmedo-Galindo JTerron-Barbosa RYCamara-Sola EValderas JMNavarro-Tausiet MPHernandez-Bono AGarcia-Alvarez JCDiez-Manglano JGutierrez-Ocana EMartinez-Manero ACamats-Franco CNavarro-Aznarez GEscobar-Perez APeleato-Sanchez JMorcillo-Cebolla SMahuela LLopez-Olmeda CSanchez-Fernandez YBSerrano-Guerra FJMunoz-Molina MDPRojas-Giraldo MJRogero-Blanco MGallego-Castillo ENMorales-Cobos LEFuster-Tozer MSanchez-Perruca LAres-Blanco SGarcia-Ocana RSalazar-Gonzalez EPJuan-Tordesillas NAlonso-Valbuena APascual-Franco MRossignoli-Fernandez TMoreno-Fernandez JCBunuel-Granados JMSerrano-Gonzalez CFernandez-Vargas AMRabanal-Basalo AOrellana-Lozano FJSanz-Pozo BMartinez-Rios INaya-Mateu YLopez-Echevarria MTardaguila-Lobato PSanchez-Silvestre AGinel-Mendoza LGarcia-Rodriguez FGonzalez-Garcia VPenuela-Ruiz TRodriguez-De-Mingo EAlmagro-Martin-Lomena MVBarrio-Higelmo ERodriguez-Rivera MRMartinez-Ayala ESeara-Lozano MLCotillas-Rodero AHernandez-Santiago VPinel-Gonzalez MMuth CMateo-Fernandez RPrados-Torres JDGarcia-Galeano MCPerez-De-Colosia-Zuil ARotaeche-Del-Campo RHazanas-Ruiz SRubio-Gutierrez IRamos-Blanco ARodriguez-Garcia CGuerrero-Fernandez-de-Alba IMorales-Ortiz FMataix-San-Juan ALopez-Aylon RMAza-Pascual-Salcedo JIHerrero-Solsona PSanz-Burgos LDrak-Hernandez YMedina-Garcia RLeiva-Fernandez FRodriguez-Gonzalez MIPascual-de-la-Pisa BLeiva-Fernandez JPoblador-Plou BArizon-Deza PBarrera-Linares FValverde-Aranda SLeon-Martinez MPMerino-Moyano MDGimeno-Miguel ACinta-Bella BMoreno-Juste ACortes-Duran PMPrados-Torres AGuiu-Campos MGonzalez-Rubio FMunoz-Gomez BLopez-Larrayoz IPico-Soler VPeyman-Fard-Shafi-Tabatabaei NAbad-Royo MSanjuan-Cortes MREsteban-Gimeno ABLopez-Villalvilla AClemente-Jimenez MLGonzalez-Hevilla ARedondo-Romero RMOrozco-Barrenechea LRodriguez-Moreno SRollan-Hernandez MLAAriza-Cardiel MGRodriguez-Fernandez MDCSanchez-Yepez JDSantos-Franco LBedoya-Frutos MJSanchez-Celaya-Del-Pozo CAlcober-Perez CGil-Conesa MMichel-Bertevas HZafra-De-Gea MBRuiz-Ciudad MCMur-Lazuela MJSepulveda-Munoz JRuiz-San-Basilio JMRumayor-Zarzuelo MMoral-Merchan MCMielgo-Salvador RGomez-Barroso MSanz-Velasco COrellana-Martin LMaqueda RAPerez-Gutierrez EInnerarity-Martinez JSanz-Cuesta TCastillo-Romero VLopez-Marcos CfalseEffectiveness of the MULTIPAP Plus intervention in youngest-old patients with multimorbidity and polypharmacy aimed at improving prescribing practices in primary care: study protocol of a cluster randomized trial.<h4>Background</h4>The progressive ageing of the population is leading to an increase in multimorbidity and polypharmacy, which in turn may increase the risk of hospitalization and mortality. The enhancement of care with information and communications technology (ICT) can facilitate the use of prescription evaluation tools and support system for decision-making (DSS) with the potential of optimizing the healthcare delivery process.<h4>Objective</h4>To assess the effectiveness and cost-effectiveness of the complex intervention MULTIPAP Plus, compared to usual care, in improving prescriptions for young-old patients (65-74 years old) with multimorbidity and polypharmacy in primary care.<h4>Methods/design</h4>This is a pragmatic cluster-randomized clinical trial with a follow-up of 18 months i2022-01-01T00:00:00Z2022 Jun2026-05-27T20:28:18.714Z2025-02-19T02:44:00.661ZS-EPMC91785303568122410.1186/s13063-022-06293-x