biostudies-literatureFan HNIBIB NIH HHSNIA NIH HHSNIDCD NIH HHSNINDS NIH HHSNIH HHS2016-2025https://www.ebi.ac.uk/biostudies/studies/S-EPMC9179092biostudies-literatureUnknown53(6)<h4>Background</h4>Perfusion and structural imaging play an important role in ischemic stroke. Magnetic resonance fingerprinting (MRF) arterial spin labeling (ASL) is a novel noninvasive method of ASL perfusion that allows simultaneous estimation of cerebral blood flow (CBF), bolus arrival time (BAT), and tissue T₁ map in a single scan of <4 minutes. Here, we evaluated the utility of MRF-ASL in patients with ischemic stroke in terms of detecting hemodynamic and structural damage and predicting neurological deficits and disability.<h4>Methods</h4>A total of 34 patients were scanned on 3T magnetic resonance imaging. MRF-ASL, standard single-delay pseudo-continuous ASL, T₂-weighted, and diffusion magnetic resonance imaging were performed. Regions of interest of lesion anStrokeSimultaneous Hemodynamic and Structural Imaging of Ischemic Stroke With Magnetic Resonance Fingerprinting Arterial Spin Labeling.PMC9179092R01 AG064792RF1 AG071515R01 NS106711UF1 NS100588R01 DC005375R01 NS106702R01 DC015466S10 OD021648P41 EB031771Fan HSu PLu HWalker ALeigh RLin DDMHillis AEGoldberg EBfalseSimultaneous Hemodynamic and Structural Imaging of Ischemic Stroke With Magnetic Resonance Fingerprinting Arterial Spin Labeling.<h4>Background</h4>Perfusion and structural imaging play an important role in ischemic stroke. Magnetic resonance fingerprinting (MRF) arterial spin labeling (ASL) is a novel noninvasive method of ASL perfusion that allows simultaneous estimation of cerebral blood flow (CBF), bolus arrival time (BAT), and tissue T₁ map in a single scan of <4 minutes. Here, we evaluated the utility of MRF-ASL in patients with ischemic stroke in terms of detecting hemodynamic and structural damage and predicting neurological deficits and disability.<h4>Methods</h4>A total of 34 patients were scanned on 3T magnetic resonance imaging. MRF-ASL, standard single-delay pseudo-continuous ASL, T₂-weighted, and diffusion magnetic resonance imaging were performed. Regions of interest of lesion an2022-01-01T00:00:00Z2022 Jun2025-04-19T08:08:46.022Z2025-04-19T08:08:46.022ZS-EPMC91790923529182010.1161/STROKEAHA.121.03706610.1161/strokeaha.121.037066