biostudies-literatureEvans SBirmingham Women's and Children's Hospital Charities Research Foundation2182https://www.ebi.ac.uk/biostudies/studies/S-EPMC9182776biostudies-literatureUnknown14(11)Patients with phenylketonuria (PKU) require a phenylalanine/protein-restricted diet, with limited food choice. Interpreting food labels, calculating protein intake, and determining food suitability are complex and confusing tasks. A mobile multi-media low-protein diet app was developed to guide food choice, label interpretation, and protein calculation. '<i>PKU Bite</i>'<sup>®</sup> includes >1100 specialist and regular low-protein foods, is colour-coded for suitability, and features a protein calculator. A 12-week randomised controlled trial assessed app efficacy, compared with written/pictorial material, in 60 parents/caregivers of children with PKU, aged 1-16 years, and 21 adolescents with PKU. Questionnaires examined self-efficacy and label-reading knowledge; food records evaluated NutrientsEfficacy of a New Low-Protein Multimedia Diet App for PKU.PMC9182776BCHRF477MacDonald ADhadwar PPinto AJackson RDaly ALecocq OEvans SSyed AAshmore CfalseEfficacy of a New Low-Protein Multimedia Diet App for PKU.Patients with phenylketonuria (PKU) require a phenylalanine/protein-restricted diet, with limited food choice. Interpreting food labels, calculating protein intake, and determining food suitability are complex and confusing tasks. A mobile multi-media low-protein diet app was developed to guide food choice, label interpretation, and protein calculation. '<i>PKU Bite</i>'<sup>®</sup> includes >1100 specialist and regular low-protein foods, is colour-coded for suitability, and features a protein calculator. A 12-week randomised controlled trial assessed app efficacy, compared with written/pictorial material, in 60 parents/caregivers of children with PKU, aged 1-16 years, and 21 adolescents with PKU. Questionnaires examined self-efficacy and label-reading knowledge; food records evaluated 2022-01-01T00:00:00Z2022 May2025-04-04T20:41:48.979Z2025-04-04T20:41:48.979ZS-EPMC91827763568398210.3390/nu14112182