{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Scaravilli V"],"funding":["Ministero dell'Università e della Ricerca","Ministero dell&apos;Università e della Ricerca"],"pagination":["176"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9191402"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(1)"],"pubmed_abstract":["<h4>Objective</h4>To assess the impact of treatment with steroids on the incidence and outcome of ventilator-associated pneumonia (VAP) in mechanically ventilated COVID-19 patients.<h4>Design</h4>Propensity-matched retrospective cohort study from February 24 to December 31, 2020, in 4 dedicated COVID-19 Intensive Care Units (ICU) in Lombardy (Italy).<h4>Patients</h4>Adult consecutive mechanically ventilated COVID-19 patients were subdivided into two groups: (1) treated with low-dose corticosteroids (dexamethasone 6 mg/day intravenous for 10 days) (DEXA+); (2) not treated with corticosteroids (DEXA-). A propensity score matching procedure (1:1 ratio) identified patients' cohorts based on: age, weight, PEEP Level, PaO<sub>2</sub>/FiO<sub>2</sub> ratio, non-respiratory Sequential Organ Failur"],"journal":["Critical care (London, England)"],"pubmed_title":["Impact of dexamethasone on the incidence of ventilator-associated pneumonia in mechanically ventilated COVID-19 patients: a propensity-matched cohort study."],"pmcid":["PMC9191402"],"funding_grant_id":["Ricerca Finalizzata project COVID-2020-12371675 &quot;COVID19: EPIDEMIOLOGICAL, CLINICAL, GENETIC, AND SOCIAL DETERMINANTS OF INFECTION AND DISEASE PROGRESSION&quot;","Ricerca Finalizzata project COVID-2020-12371675 \"COVID19: EPIDEMIOLOGICAL, CLINICAL, GENETIC, AND SOCIAL DETERMINANTS OF INFECTION AND DISEASE PROGRESSION\""],"pubmed_authors":["Grasselli G","Bellani G","Greco M","Scaravilli V","Monti G","Guzzardella A","Beltrama V","Muscatello A","Bandera A","Pesenti A","Madotto F"],"additional_accession":[]},"is_claimable":false,"name":"Impact of dexamethasone on the incidence of ventilator-associated pneumonia in mechanically ventilated COVID-19 patients: a propensity-matched cohort study.","description":"<h4>Objective</h4>To assess the impact of treatment with steroids on the incidence and outcome of ventilator-associated pneumonia (VAP) in mechanically ventilated COVID-19 patients.<h4>Design</h4>Propensity-matched retrospective cohort study from February 24 to December 31, 2020, in 4 dedicated COVID-19 Intensive Care Units (ICU) in Lombardy (Italy).<h4>Patients</h4>Adult consecutive mechanically ventilated COVID-19 patients were subdivided into two groups: (1) treated with low-dose corticosteroids (dexamethasone 6 mg/day intravenous for 10 days) (DEXA+); (2) not treated with corticosteroids (DEXA-). A propensity score matching procedure (1:1 ratio) identified patients' cohorts based on: age, weight, PEEP Level, PaO<sub>2</sub>/FiO<sub>2</sub> ratio, non-respiratory Sequential Organ Failur","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2026-05-29T01:05:12.79Z","creation":"2025-04-05T20:40:26.189Z"},"accession":"S-EPMC9191402","cross_references":{"pubmed":["35698155"],"doi":["10.1186/s13054-022-04049-2"]}}