biostudies-literatureMay PANational Institute on Alcohol Abuse and AlcoholismNIAAA NIH HHSNational Institutes of Health2019-2035https://www.ebi.ac.uk/biostudies/studies/S-EPMC9197851biostudies-literatureUnknown188(7)We compared growth, physical features, and minor anomalies in 131 first-grade children with fetal alcohol spectrum disorders (FASD) to those of a representative comparison group of typically developing children from the same populations (n = 1212). The data were collected from three regional sites in the NIAAA-funded Collaboration on FASD Prevalence (CoFASP). Dysmorphology examinations were performed by a team of expert clinical geneticists, and FASD diagnoses were assigned according to the Revised Institute of Medicine Guidelines, which include assessments of growth, dysmorphology, neurobehavior, and maternal risk interviews. We present detailed data on 32 physical traits, minor anomalies, and a summary dysmorphology score for children within each of the four diagnostic categories in the American journal of medical genetics. Part ACharacteristic physical traits of first-grade children in the United States with fetal alcohol spectrum disorders (FASD) and associated alcohol and drug exposures.PMC9197851U01 AA019894Hoyme HEAdam MPBuckley DRobinson LKElliott AJManning MAKalberg WOAbdul-Rahman OMay PAHasken JMJewett TfalseCharacteristic physical traits of first-grade children in the United States with fetal alcohol spectrum disorders (FASD) and associated alcohol and drug exposures.We compared growth, physical features, and minor anomalies in 131 first-grade children with fetal alcohol spectrum disorders (FASD) to those of a representative comparison group of typically developing children from the same populations (n = 1212). The data were collected from three regional sites in the NIAAA-funded Collaboration on FASD Prevalence (CoFASP). Dysmorphology examinations were performed by a team of expert clinical geneticists, and FASD diagnoses were assigned according to the Revised Institute of Medicine Guidelines, which include assessments of growth, dysmorphology, neurobehavior, and maternal risk interviews. We present detailed data on 32 physical traits, minor anomalies, and a summary dysmorphology score for children within each of the four diagnostic categories in the 2022-01-01T00:00:00Z2022 Jul2025-04-26T07:39:07.792Z2025-04-06T12:21:59.133ZS-EPMC91978513535707510.1002/ajmg.a.62738