<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Fagundes NCF</submitter><funding>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior</funding><funding>American Association of Orthodontists Foundation</funding><pagination>e061651</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC9204397</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>12(6)</volume><pubmed_abstract>&lt;h4>Introduction&lt;/h4>Obstructive sleep apnoea (OSA) is a sleep-breathing disorder that seems likely to have long-term negative social and health consequences in children and adolescents. There are no established standard management approaches when the first line of therapy, the tonsillectomy and adenoidectomy (T&amp;A), is not indicated or fails to address paediatric OSA (residual paediatric OSA). This protocol describes a prospective cohort study that aims to assess the effectiveness of orthodontic interventions for managing residual paediatric OSA in patients with concomitant craniofacial issues.&lt;h4>Methods and analysis&lt;/h4>Children aged 6-16 years who with an OSA diagnosis and did not benefit from previous T&amp;A or qualified for T&amp;A will be recruited. Orthodontic intervention(s), when adequat</pubmed_abstract><journal>BMJ open</journal><pubmed_title>Orthodontic interventions as a management option for children with residual obstructive sleep apnea: a cohort study protocol.</pubmed_title><pmcid>PMC9204397</pmcid><funding_grant_id>N/A</funding_grant_id><funding_grant_id>88881.128202/2016-01</funding_grant_id><pubmed_authors>Fagundes NCF</pubmed_authors><pubmed_authors>Perez-Garcia A</pubmed_authors><pubmed_authors>Graf D</pubmed_authors><pubmed_authors>Flores-Mir C</pubmed_authors><pubmed_authors>Heo G</pubmed_authors></additional><is_claimable>false</is_claimable><name>Orthodontic interventions as a management option for children with residual obstructive sleep apnea: a cohort study protocol.</name><description>&lt;h4>Introduction&lt;/h4>Obstructive sleep apnoea (OSA) is a sleep-breathing disorder that seems likely to have long-term negative social and health consequences in children and adolescents. There are no established standard management approaches when the first line of therapy, the tonsillectomy and adenoidectomy (T&amp;A), is not indicated or fails to address paediatric OSA (residual paediatric OSA). This protocol describes a prospective cohort study that aims to assess the effectiveness of orthodontic interventions for managing residual paediatric OSA in patients with concomitant craniofacial issues.&lt;h4>Methods and analysis&lt;/h4>Children aged 6-16 years who with an OSA diagnosis and did not benefit from previous T&amp;A or qualified for T&amp;A will be recruited. Orthodontic intervention(s), when adequat</description><dates><release>2022-01-01T00:00:00Z</release><publication>2022 Jun</publication><modification>2026-05-27T19:24:43.434Z</modification><creation>2022-07-08T07:41:29.37Z</creation></dates><accession>S-EPMC9204397</accession><cross_references><pubmed>35705345</pubmed><doi>10.1136/bmjopen-2022-061651</doi></cross_references></HashMap>