{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Morrow AJ"],"funding":["British Heart Foundation","Medical Research Council","Chief Scientist Office"],"pagination":["1303-1313"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9205780"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["28(6)"],"pubmed_abstract":["The pathophysiology and trajectory of post-Coronavirus Disease 2019 (COVID-19) syndrome is uncertain. To clarify multisystem involvement, we undertook a prospective cohort study including patients who had been hospitalized with COVID-19 (ClinicalTrials.gov ID NCT04403607 ). Serial blood biomarkers, digital electrocardiography and patient-reported outcome measures were obtained in-hospital and at 28-60 days post-discharge when multisystem imaging using chest computed tomography with pulmonary and coronary angiography and cardio-renal magnetic resonance imaging was also obtained. Longer-term clinical outcomes were assessed using electronic health records. Compared to controls (n = 29), at 28-60 days post-discharge, people with COVID-19 (n = 159; mean age, 55 years; 43% female) had persisting"],"journal":["Nature medicine"],"pubmed_title":["A multisystem, cardio-renal investigation of post-COVID-19 illness."],"pmcid":["PMC9205780"],"funding_grant_id":["311300","MC_PC_19026","RE/18/6134217"],"pubmed_authors":["Brown A","Rankin AJ","Morrow AJ","McGinley C","Dougherty A","Lang NN","McConnachie A","Dobbin SJH","CISCO-19 Consortium","Hall Barrientos P","Grieve D","Robertson KE","Watkins S","McIntosh A","Gibson VB","Touyz RM","Gilmour L","Blyth KG","Fallon K","Berry C","Ho A","Bulluck H","Lowe DJ","Hopkins T","Briscoe M","Sykes R","Carrick D","Macfarlane PW","Church C","Mark PB","McGeoch R","Welsh P","Savage F","Nordin S","Basu N","Tynan N","Ryan N","Dymock L","Siebert S","Lennie V","Weir RA","Weeden S","McLennan E","Sattar N","Gillespie L","Findlay I","Stobo D","Corcoran D","Allwood-Spiers S","McKee C","Butler E","Roditi G","Woodward R","Veldtman G","Mayne KJ","Bagot C","McInnes IB","Bayes HK","Payne A","Mangion K","Lees JS","Kamdar A","Wereski R"],"additional_accession":[]},"is_claimable":false,"name":"A multisystem, cardio-renal investigation of post-COVID-19 illness.","description":"The pathophysiology and trajectory of post-Coronavirus Disease 2019 (COVID-19) syndrome is uncertain. To clarify multisystem involvement, we undertook a prospective cohort study including patients who had been hospitalized with COVID-19 (ClinicalTrials.gov ID NCT04403607 ). Serial blood biomarkers, digital electrocardiography and patient-reported outcome measures were obtained in-hospital and at 28-60 days post-discharge when multisystem imaging using chest computed tomography with pulmonary and coronary angiography and cardio-renal magnetic resonance imaging was also obtained. Longer-term clinical outcomes were assessed using electronic health records. Compared to controls (n = 29), at 28-60 days post-discharge, people with COVID-19 (n = 159; mean age, 55 years; 43% female) had persisting","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2026-05-10T01:41:14.245Z","creation":"2025-02-19T02:57:49.435Z"},"accession":"S-EPMC9205780","cross_references":{"pubmed":["35606551"],"doi":["10.1038/s41591-022-01837-9"]}}