biostudies-literatureUnknown22(1)Kherabi Y<h4>Background</h4>Staphylococci and streptococci are the most frequent pathogens isolated from prosthetic joint infections (PJIs). The aim of this study was to analyze the outcome of streptococcal and methicillin-susceptible Staphylococcus aureus (MSSA) PJIs.<h4>Methods</h4>All monomicrobial streptococcal and MSSA PJIs managed in a French Referral Center (2010-2017) were sampled from the prospective PJIs cohort study. The primary outcome of interest was the cumulative reinfection-free survival at a 2-year follow-up.<h4>Results</h4>Two hundred and nine patients with 91 streptococcal and 132 staphylococcal infections were analyzed. Patients with streptococcal PJI were older, and infection was more frequently hematogenous. Reinfection-free survival rates at 2-years after all treatment strateBMC infectious diseases555https://www.ebi.ac.uk/biostudies/studies/S-EPMC9206280biostudies-literatureStreptococcal and Staphylococcus aureus prosthetic joint infections: are they really different?PMC9206280Meyssonnier VZeller VMarmor SHeym BLidove OKerroumi YKherabi YfalseStreptococcal and Staphylococcus aureus prosthetic joint infections: are they really different?<h4>Background</h4>Staphylococci and streptococci are the most frequent pathogens isolated from prosthetic joint infections (PJIs). The aim of this study was to analyze the outcome of streptococcal and methicillin-susceptible Staphylococcus aureus (MSSA) PJIs.<h4>Methods</h4>All monomicrobial streptococcal and MSSA PJIs managed in a French Referral Center (2010-2017) were sampled from the prospective PJIs cohort study. The primary outcome of interest was the cumulative reinfection-free survival at a 2-year follow-up.<h4>Results</h4>Two hundred and nine patients with 91 streptococcal and 132 staphylococcal infections were analyzed. Patients with streptococcal PJI were older, and infection was more frequently hematogenous. Reinfection-free survival rates at 2-years after all treatment strate2022-01-01T00:00:00Z2022 Jun2025-04-05T16:14:35.148Z2025-04-05T16:14:35.148ZS-EPMC92062803571575410.1186/s12879-022-07532-x