{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Fang H"],"funding":["National Key Research and Development Program of China"],"pubmed_abstract":["Though some freshwater fish have been successfully cultivated in saline-alkali water, the survival rates of freshwater fish are greatly affected by different saline-alkali conditions. The mechanisms of immune adaptation or immunosuppression of freshwater fish under different saline-alkali stress remain unclear. Here, grass carp were exposed to 3‰ and 6‰ salinity for 30 days. It was observed that salinity treatments had no obvious effects on survival rates, but significantly increased the percent of unhealthy fish. Salinity treatments also increased the susceptibility of grass carp against <i>Flavobacterium columnare</i> infection. The fatality rate (16.67%) of grass carp treated with 6‰ salinity was much lower than that treated with 3‰ salinity (40%). In the absence of infection, higher nu"],"journal":["Frontiers in immunology"],"pagination":["917497"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9207326"],"repository":["biostudies-literature"],"pubmed_title":["Effects and Molecular Regulation Mechanisms of Salinity Stress on the Health and Disease Resistance of Grass Carp."],"pmcid":["PMC9207326"],"pubmed_authors":["Song YJ","Fang H","Yang YY","Zhang J","Wu XM","Chang MX","Zheng SY"],"additional_accession":[]},"is_claimable":false,"name":"Effects and Molecular Regulation Mechanisms of Salinity Stress on the Health and Disease Resistance of Grass Carp.","description":"Though some freshwater fish have been successfully cultivated in saline-alkali water, the survival rates of freshwater fish are greatly affected by different saline-alkali conditions. The mechanisms of immune adaptation or immunosuppression of freshwater fish under different saline-alkali stress remain unclear. Here, grass carp were exposed to 3‰ and 6‰ salinity for 30 days. It was observed that salinity treatments had no obvious effects on survival rates, but significantly increased the percent of unhealthy fish. Salinity treatments also increased the susceptibility of grass carp against <i>Flavobacterium columnare</i> infection. The fatality rate (16.67%) of grass carp treated with 6‰ salinity was much lower than that treated with 3‰ salinity (40%). In the absence of infection, higher nu","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-06-19T03:15:52.896Z","creation":"2024-11-05T20:35:23.678Z"},"accession":"S-EPMC9207326","cross_references":{"pubmed":["35734166"],"doi":["10.3389/fimmu.2022.917497"]}}