{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tseng PT"],"funding":["National Institute for Health Research (NIHR)"],"pagination":["770-779"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9218931"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["79(8)"],"pubmed_abstract":["<h4>Importance</h4>Negative symptoms have a detrimental impact on functional outcomes and quality of life in people with schizophrenia, and few therapeutic options are considered effective for this symptomatic dimension. Studies have suggested that noninvasive brain stimulation (NIBS) interventions may be effective in treating negative symptoms. However, the comparative efficacy of different NIBS protocols for relieving negative symptoms remains unclear.<h4>Objective</h4>To compare the efficacy and acceptability of different NIBS interventions for treating negative symptoms.<h4>Data sources</h4>The ClinicalKey, Cochrane CENTRAL, Embase, ProQuest, PubMed, ScienceDirect, ClinicalTrials.gov, and Web of Science electronic databases were systematically searched from inception through December 7"],"journal":["JAMA psychiatry"],"pubmed_title":["Assessment of Noninvasive Brain Stimulation Interventions for Negative Symptoms of Schizophrenia: A Systematic Review and Network Meta-analysis."],"pmcid":["PMC9218931"],"funding_grant_id":["NIHR301206"],"pubmed_authors":["Hung CM","Tseng PT","Su KP","Tu YK","Yang WC","Zeng BS","Chen YW","Li CT","Chen TY","Satogami K","Hsu CW","Stubbs B","Lin PY","Suen MW","Wu YC","Takahashi S","Wu CK","Carvalho AF","Li DJ","Brunoni AR","Liang CS","Shiue YL","Huang TL"],"additional_accession":[]},"is_claimable":false,"name":"Assessment of Noninvasive Brain Stimulation Interventions for Negative Symptoms of Schizophrenia: A Systematic Review and Network Meta-analysis.","description":"<h4>Importance</h4>Negative symptoms have a detrimental impact on functional outcomes and quality of life in people with schizophrenia, and few therapeutic options are considered effective for this symptomatic dimension. Studies have suggested that noninvasive brain stimulation (NIBS) interventions may be effective in treating negative symptoms. However, the comparative efficacy of different NIBS protocols for relieving negative symptoms remains unclear.<h4>Objective</h4>To compare the efficacy and acceptability of different NIBS interventions for treating negative symptoms.<h4>Data sources</h4>The ClinicalKey, Cochrane CENTRAL, Embase, ProQuest, PubMed, ScienceDirect, ClinicalTrials.gov, and Web of Science electronic databases were systematically searched from inception through December 7","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-05T14:46:19.592Z","creation":"2025-04-05T14:46:19.592Z"},"accession":"S-EPMC9218931","cross_references":{"pubmed":["35731533"],"doi":["10.1001/jamapsychiatry.2022.1513"]}}