biostudies-literatureUnknown19(12)Kuzan AMedical care for geriatric patients is a great challenge, mainly due to various overlapping deficits relevant to numerous coexisting diseases, of which the most common are diabetes mellitus and atherosclerosis. In the case of diabetes, the glycation process is intensified, which accelerates atherosclerosis development and diabetic complications. Our goal was to investigate the relationship between the classical biochemical parameters of diabetes and atherosclerosis, as well as parameters which may indicate a nephropathy, and the parameters strictly related to glycation, taking into account the pharmacological treatment of patients. Methods: We analyzed the patients' serum concentrations of fluorescent glycation product-pentosidine, concentrations of soluble receptors for advanced glycationInternational journal of environmental research and public health7524https://www.ebi.ac.uk/biostudies/studies/S-EPMC9223786biostudies-literatureHow Diabetes and Other Comorbidities of Elderly Patients and Their Treatment Influence Levels of Glycation Products.PMC9223786Kuzan AKustrzeba-Wojcicka IKrolewicz ESobieszczanska MLindner-Pawlowicz KfalseHow Diabetes and Other Comorbidities of Elderly Patients and Their Treatment Influence Levels of Glycation Products.Medical care for geriatric patients is a great challenge, mainly due to various overlapping deficits relevant to numerous coexisting diseases, of which the most common are diabetes mellitus and atherosclerosis. In the case of diabetes, the glycation process is intensified, which accelerates atherosclerosis development and diabetic complications. Our goal was to investigate the relationship between the classical biochemical parameters of diabetes and atherosclerosis, as well as parameters which may indicate a nephropathy, and the parameters strictly related to glycation, taking into account the pharmacological treatment of patients. Methods: We analyzed the patients' serum concentrations of fluorescent glycation product-pentosidine, concentrations of soluble receptors for advanced glycation2022-01-01T00:00:00Z2022 Jun2025-04-26T16:04:13.612Z2024-12-03T18:41:14.605ZS-EPMC92237863574277610.3390/ijerph19127524