{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jarosz A"],"funding":["Medical University of Silesia in Katowice","Medical University of Silesia"],"pagination":["3504"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9224593"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(12)"],"pubmed_abstract":["<h4>Background</h4>This study aims to identify genotype variants of the platelet-derived growth factor alpha polypeptide gene (<i>PDGFA</i>) that can influence the individual response to the treatment with platelet-rich plasma (PRP) in tennis elbow patients.<h4>Methods</h4>We observed a cohort of 107 patients (132 elbows) with tennis elbow who received treatment with PRP. Patients have been followed-up for two years after PRP injection and the effectiveness of the treatment was measured using universal patient-reported outcome measures (PROMs): visual analog scale (VAS), quick version of disabilities of the arm, shoulder and hand score (QDASH), and patient-rated tennis elbow evaluation (PRTEE). PROMs values, and clinical and platelet parameters were compared between genotype variants of th"],"journal":["Journal of clinical medicine"],"pubmed_title":["What Role Does <i>PDGFA</i> Gene Polymorphisms Play in Treating Tennis Elbow with PRP? A Prospective Cohort Study."],"pmcid":["PMC9224593"],"funding_grant_id":["PCN-1-071/K/0/Z","PCN-1-096/K/1/Z"],"pubmed_authors":["Balcerzyk A","Negru M","Gorczynska-Kosiorz S","Garczorz W","Szyluk K","Iwanicka J","Kalita M","Jarosz A","Francuz T","Iwanicki T","Niemiec P","Nowak T","Kania W"],"additional_accession":[]},"is_claimable":false,"name":"What Role Does <i>PDGFA</i> Gene Polymorphisms Play in Treating Tennis Elbow with PRP? A Prospective Cohort Study.","description":"<h4>Background</h4>This study aims to identify genotype variants of the platelet-derived growth factor alpha polypeptide gene (<i>PDGFA</i>) that can influence the individual response to the treatment with platelet-rich plasma (PRP) in tennis elbow patients.<h4>Methods</h4>We observed a cohort of 107 patients (132 elbows) with tennis elbow who received treatment with PRP. Patients have been followed-up for two years after PRP injection and the effectiveness of the treatment was measured using universal patient-reported outcome measures (PROMs): visual analog scale (VAS), quick version of disabilities of the arm, shoulder and hand score (QDASH), and patient-rated tennis elbow evaluation (PRTEE). PROMs values, and clinical and platelet parameters were compared between genotype variants of th","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2026-05-07T03:08:10.468Z","creation":"2025-02-19T02:58:33.612Z"},"accession":"S-EPMC9224593","cross_references":{"pubmed":["35743573"],"doi":["10.3390/jcm11123504"]}}