{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hong C"],"funding":["National Center for Advancing Translational Sciences","National Institute of Neurological Disorders and Stroke","NCATS NIH HHS","NICHD NIH HHS","National Medical Research Council Research Training Fellowship","U.S. National Library of Medicine","NIEHS NIH HHS","NHLBI NIH HHS","National Heart, Lung, and Blood Institute","National Institutes of Health","National Human Genome Research Institute","Carlos III Health Institute","NHGRI NIH HHS","NLM NIH HHS","NCI NIH HHS","NINDS NIH HHS"],"pagination":["e057725"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9226470"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(6)"],"pubmed_abstract":["<h4>Objective</h4>To assess changes in international mortality rates and laboratory recovery rates during hospitalisation for patients hospitalised with SARS-CoV-2 between the first wave (1 March to 30 June 2020) and the second wave (1 July 2020 to 31 January 2021) of the COVID-19 pandemic.<h4>Design, setting and participants</h4>This is a retrospective cohort study of 83 178 hospitalised patients admitted between 7 days before or 14 days after PCR-confirmed SARS-CoV-2 infection within the Consortium for Clinical Characterization of COVID-19 by Electronic Health Record, an international multihealthcare system collaborative of 288 hospitals in the USA and Europe. The laboratory recovery rates and mortality rates over time were compared between the two waves of the pandemic.<h4>Primary and s"],"journal":["BMJ open"],"pubmed_title":["Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS-CoV-2."],"pmcid":["PMC9226470"],"funding_grant_id":["UL1TR001420","R01 LM013337","P30ES017885","R01LM012095","UL1TR001881","UL1 TR001420","UL1 TR001881","T15 LM007092","R01 HL151643","T32 HD040128","R01 NS124882","MOH-000195-00","U24 CA210967","P30 ES017885","U24CA210967","U01 HG008685","L40 HL148910","CTSA UL1-TR001878","R01 HG009174","R01NS098023","R01LM013345","UL1TR001857","PI18/00981","R01 LM013345","UL1 TR002240","UL1TR002541","UL1 TR002366","UL1TR000005","UL1 TR002541","UL1TR002240","UL1 TR001998","L40HL148910","UL1 TR000005","3U01HG008685-05S2","UL1 TR001857","UL1 TR001878","CTSA UL1TR002366","K23HL148394","CTSA UL1TR001998","5R01HG009174-04","K23 HL148394","R01 LM012095","5UL1TR001857-05","R01 HL151643-01","R01 NS098023"],"pubmed_authors":["Tibollo V","Serrano-Balazote P","Ho YL","Schubert P","Bonzel CL","Schriver ER","Consortium for Clinical Characterization of COVID-19 by EHR (4CE)","Brat GA","Palmer NP","Hutch MR","Wang X","Omenn GS","Yuan W","Chiovato L","Klann J","Xia Z","Zhang HG","Sanz Vidorreta FJ","Bourgeois F","Samayamuthu MJ","Patel LP","Bellazzi R","Maidlow S","South A","Le TT","Gutierrez-Sacristan A","L'Yi S","Ngiam KY","Neuraz A","Cai T","Wagholikar K","Liu M","Pedrera-Jimenez M","Zoller D","Tan ALM","Holmes JH","Tan BWQ","Kohane I","Dagliati A","Kavuluru R","Cho K","Morris M","Tan BWL","Follett RW","Murphy S","Gehlenborg N","Garcia-Barrio N","Benoit V","Moal B","Lozano-Zahonero S","Weber G","Visweswaran S","Mowery DL","Malovini A","Makoudjou A","Beaulieu-Jones BK","Tippmann P","Estiri H","Hong C","Hanauer DA","Luo Y","Avillach P"],"additional_accession":[]},"is_claimable":false,"name":"Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS-CoV-2.","description":"<h4>Objective</h4>To assess changes in international mortality rates and laboratory recovery rates during hospitalisation for patients hospitalised with SARS-CoV-2 between the first wave (1 March to 30 June 2020) and the second wave (1 July 2020 to 31 January 2021) of the COVID-19 pandemic.<h4>Design, setting and participants</h4>This is a retrospective cohort study of 83 178 hospitalised patients admitted between 7 days before or 14 days after PCR-confirmed SARS-CoV-2 infection within the Consortium for Clinical Characterization of COVID-19 by Electronic Health Record, an international multihealthcare system collaborative of 288 hospitals in the USA and Europe. The laboratory recovery rates and mortality rates over time were compared between the two waves of the pandemic.<h4>Primary and s","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2026-05-27T19:48:47.306Z","creation":"2022-07-11T02:47:57.203Z"},"accession":"S-EPMC9226470","cross_references":{"pubmed":["35738646"],"doi":["10.1136/bmjopen-2021-057725"]}}