{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Muilu-Makela R"],"funding":["Environmental Ministry of Finland","Strategic internal Funding of Natural Resources Institute Finland","European Regional Development Fund"],"pagination":["3891"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9230896"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(12)"],"pubmed_abstract":["Volatile organic compounds (VOC) affect the quality of indoor air. Terpenes and especially monoterpenes are the main molecules emitted from softwood material (coniferous species), which is widely used in construction. The corneal epithelium is one of the first human membranes to encounter VOCs in the air. Moreover, the industrial use of pleasant-scented monoterpenes in cosmetics, food, and detergents exposes people to monoterpenes in their daily lives. In the present study, the health effective properties of five monoterpenes from softwood were tested; cytotoxicity and oxidative stress-protective effects of α- and β-pinenes, R- and S-limonene, and 3-carene were tested in a human corneal epithelial (HCE) cell model system and with two additional in vitro antioxidant tests: oxygen radical ab"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Antibacterial and Oxidative Stress-Protective Effects of Five Monoterpenes from Softwood."],"pmcid":["PMC9230896"],"funding_grant_id":["VN/2884/2019","41007-00096900","A71142"],"pubmed_authors":["Uusitalo H","Tienaho J","Sarjala T","Muilu-Makela R","Aapola U"],"additional_accession":[]},"is_claimable":false,"name":"Antibacterial and Oxidative Stress-Protective Effects of Five Monoterpenes from Softwood.","description":"Volatile organic compounds (VOC) affect the quality of indoor air. Terpenes and especially monoterpenes are the main molecules emitted from softwood material (coniferous species), which is widely used in construction. The corneal epithelium is one of the first human membranes to encounter VOCs in the air. Moreover, the industrial use of pleasant-scented monoterpenes in cosmetics, food, and detergents exposes people to monoterpenes in their daily lives. In the present study, the health effective properties of five monoterpenes from softwood were tested; cytotoxicity and oxidative stress-protective effects of α- and β-pinenes, R- and S-limonene, and 3-carene were tested in a human corneal epithelial (HCE) cell model system and with two additional in vitro antioxidant tests: oxygen radical ab","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-04T19:13:27.926Z","creation":"2025-04-04T19:13:27.926Z"},"accession":"S-EPMC9230896","cross_references":{"pubmed":["35745011"],"doi":["10.3390/molecules27123891"]}}