{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang Y"],"funding":["National Institute of Health","National Institutes of Health","National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["22-28"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9233151"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["204"],"pubmed_abstract":["A near-infrared fluorescent probe was prepared for selective detection of reduced nicotinamide adenine dinucleotide (NADH) in live cells. The probe turns off the fluorescence with a closed spironolactone switch. However, reduction of the probe by NADH turns on fluorescence at 740 nm. Theoretical calculations suggest a more planar arrangement between the rhodamine and quinoline moieties with increased π-delocalization resulting from reduction."],"journal":["Methods (San Diego, Calif.)"],"pubmed_title":["Near-infrared fluorescent probe based on rhodamine derivative for detection of NADH in live cells."],"pmcid":["PMC9233151"],"funding_grant_id":["R15 GM114751","2R15GM114751-02"],"pubmed_authors":["Olowolagba A","Liu H","Arachchige DL","Zhang Y","Luck RL"],"additional_accession":[]},"is_claimable":false,"name":"Near-infrared fluorescent probe based on rhodamine derivative for detection of NADH in live cells.","description":"A near-infrared fluorescent probe was prepared for selective detection of reduced nicotinamide adenine dinucleotide (NADH) in live cells. The probe turns off the fluorescence with a closed spironolactone switch. However, reduction of the probe by NADH turns on fluorescence at 740 nm. Theoretical calculations suggest a more planar arrangement between the rhodamine and quinoline moieties with increased π-delocalization resulting from reduction.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2025-04-04T20:07:43.31Z","creation":"2025-04-04T20:07:43.31Z"},"accession":"S-EPMC9233151","cross_references":{"pubmed":["35381337"],"doi":["10.1016/j.ymeth.2022.03.019"]}}