{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Cherubini V"],"pubmed_abstract":["<h4>Aim/hypothesis</h4>To compare the frequency of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in Italy during the COVID-19 pandemic in 2020 with the frequency of DKA during 2017-2019.<h4>Methods</h4>Forty-seven pediatric diabetes centers caring for >90% of young people with diabetes in Italy recruited 4,237 newly diagnosed children with type 1 diabetes between 2017 and 2020 in a longitudinal study. Four subperiods in 2020 were defined based on government-imposed containment measures for COVID-19, and the frequencies of DKA and severe DKA compared with the same periods in 2017-2019.<h4>Results</h4>Overall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from "],"journal":["Frontiers in endocrinology"],"pagination":["878634"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9247264"],"repository":["biostudies-literature"],"pubmed_title":["The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020."],"pmcid":["PMC9247264"],"pubmed_authors":["Ortolani F","Pozzi E","Bobbio A","Ripoli C","Gesuita R","Mozzillo E","Predieri B","Tiberi V","Mameli C","Giannini C","Zampolli M","Marigliano M","Bassi M","Cherubini V","Gallo F","Ricciardi MR","Bruzzi P","Maltoni G","De Donno V","Rigamonti A","Frontino G","Felappi B","Iannilli A","Calcaterra V","Arnaldi C","Macedoni M","Piscopo A","Tinti D","Scaramuzza AE","Tornese G","Zanfardino A","Lasagni A","Franzese A","Cauvin V","Monti S","D'Annunzio G","De Marco R","Grosso C","Zucchini S","De Sanctis L","Cardinale G","Pampanini V","Berioli MG","Moretti C","Rutigliano I","Rabbone I","Maffeis C","Schiaffini R","Franceschi R","Piccinno E","Innaurato S","Graziani V","Bracciolini GP","Guerraggio LP","Musolino G","Citriniti F","Talarico V","Bonfanti R","Piccini B","Patera PI","Pascarella F","Lombardo F","Marino M","Iovane B","Chiarelli F","Iafusco D","Minuto N","Bombaci B","Delvecchio M","Lenzi L","Curto S","Sordelli S","Cardella F","De Berardinis F","Toni S","Rosanio F","Franco F","Piredda G","Matteoli MC","Trada M","Stamati FA","Meloni G","Rollato AS","Coccioli S"],"additional_accession":[]},"is_claimable":false,"name":"The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020.","description":"<h4>Aim/hypothesis</h4>To compare the frequency of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in Italy during the COVID-19 pandemic in 2020 with the frequency of DKA during 2017-2019.<h4>Methods</h4>Forty-seven pediatric diabetes centers caring for >90% of young people with diabetes in Italy recruited 4,237 newly diagnosed children with type 1 diabetes between 2017 and 2020 in a longitudinal study. Four subperiods in 2020 were defined based on government-imposed containment measures for COVID-19, and the frequencies of DKA and severe DKA compared with the same periods in 2017-2019.<h4>Results</h4>Overall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T21:41:11.618Z","creation":"2022-07-08T07:55:50.551Z"},"accession":"S-EPMC9247264","cross_references":{"pubmed":["35784550"],"doi":["10.3389/fendo.2022.878634"]}}