biostudies-literatureUnknown22(1)Hernandez-Munoz AE<h4>Background</h4>Subjective well-being (SWB) can be defined as a self-report evaluation that reflects the satisfaction, and emotional level, over several social and personal indicators. Alterations in these indicators could become risk factors (RF) for major depressive disorder (MDD), but this association has not been studied at women's life stages such as the perimenopause onset, despite its increasing prevalence for depressive symptomatology. Therefore, the aim of this study was to identify if SWB's alterations determine RF for MDD during the perimenopause.<h4>Methods</h4>An analytical cross-sectional study was realized in 252 Mexican women with perimenopause's age range (48 ± 1.7) and menopausal symptomatology, treated on Medical Units belonging to Jalisco's 13th Health-Region. We appBMC women's health275https://www.ebi.ac.uk/biostudies/studies/S-EPMC9258048biostudies-literatureSubjective well-being's alterations as risk factors for major depressive disorder during the perimenopause onset: an analytical cross-sectional study amongst Mexican women residing in Guadalajara, Jalisco.PMC9258048Garcia LTde Jesus Lopez-Jimenez JFletes-Rayas ALRangel MAMendez-Magana AHernandez-Munoz AEfalseSubjective well-being's alterations as risk factors for major depressive disorder during the perimenopause onset: an analytical cross-sectional study amongst Mexican women residing in Guadalajara, Jalisco.<h4>Background</h4>Subjective well-being (SWB) can be defined as a self-report evaluation that reflects the satisfaction, and emotional level, over several social and personal indicators. Alterations in these indicators could become risk factors (RF) for major depressive disorder (MDD), but this association has not been studied at women's life stages such as the perimenopause onset, despite its increasing prevalence for depressive symptomatology. Therefore, the aim of this study was to identify if SWB's alterations determine RF for MDD during the perimenopause.<h4>Methods</h4>An analytical cross-sectional study was realized in 252 Mexican women with perimenopause's age range (48 ± 1.7) and menopausal symptomatology, treated on Medical Units belonging to Jalisco's 13th Health-Region. We app2022-01-01T00:00:00Z2022 Jul2025-04-19T04:43:06.115Z2022-07-23T12:17:44.403ZS-EPMC92580483579095210.1186/s12905-022-01848-1