{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jin B"],"funding":["Wellcome Trust","Army Research Laboratory","NIGMS NIH HHS","Biotechnology and Biological Sciences Research Council"],"pagination":["e202201980"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9258440"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(14)"],"pubmed_abstract":["While bio-inspired synthesis offers great potential for controlling nucleation and growth of inorganic particles, precisely tuning biomolecule-particle interactions is a long-standing challenge. Herein, we used variations in peptoid sequence to manipulate peptoid-Au interactions, leading to the synthesis of concave five-fold twinned, five-pointed Au nanostars via a process of repeated particle attachment and facet stabilization. Ex situ and liquid-phase TEM observations show that a balance between particle attachment biased to occur near the star points, preferential growth along the [100] direction, and stabilization of (111) facets is critical to forming star-shaped particles. Molecular simulations predict that interaction strengths between peptoids and distinct Au facets differ signific"],"journal":["Angewandte Chemie (International ed. in English)"],"pubmed_title":["Peptoid-Directed Formation of Five-Fold Twinned Au Nanostars through Particle Attachment and Facet Stabilization."],"pmcid":["PMC9258440"],"funding_grant_id":["W911NF1920198","BB/S003339/1","206422/Z/17/Z","P50 GM082251","R01 GM085043"],"pubmed_authors":["Chen CL","Tao J","Fu X","Naser NY","Zhang P","Cai B","DeYoreo JJ","Jin B","Qi X","Pfaendtner J","Zhang X","Tan S","Baneyx F","Yan F"],"additional_accession":[]},"is_claimable":false,"name":"Peptoid-Directed Formation of Five-Fold Twinned Au Nanostars through Particle Attachment and Facet Stabilization.","description":"While bio-inspired synthesis offers great potential for controlling nucleation and growth of inorganic particles, precisely tuning biomolecule-particle interactions is a long-standing challenge. Herein, we used variations in peptoid sequence to manipulate peptoid-Au interactions, leading to the synthesis of concave five-fold twinned, five-pointed Au nanostars via a process of repeated particle attachment and facet stabilization. Ex situ and liquid-phase TEM observations show that a balance between particle attachment biased to occur near the star points, preferential growth along the [100] direction, and stabilization of (111) facets is critical to forming star-shaped particles. Molecular simulations predict that interaction strengths between peptoids and distinct Au facets differ signific","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Mar","modification":"2025-04-05T10:45:30.894Z","creation":"2025-04-05T10:45:30.894Z"},"accession":"S-EPMC9258440","cross_references":{"pubmed":["35167709"],"doi":["10.1002/anie.202201980"]}}