biostudies-literatureJaeger BCNICHD NIH HHSNHLBI NIH HHSNIGMS NIH HHS94-101https://www.ebi.ac.uk/biostudies/studies/S-EPMC9259065biostudies-literatureUnknown40(1)<h4>Background</h4>The 2017 American College of Cardiology/American Heart Association blood pressure (BP) guideline recommends using 10-year predicted atherosclerotic cardiovascular disease (ASCVD) risk to guide decisions to initiate antihypertensive medication.<h4>Methods</h4>We included adults aged 40-79 years from the National Health and Nutrition Examination Survey 2013-2018 (n = 8803). We computed 10-year predicted ASCVD risk using the Pooled Cohort risk equations. Clinical CVD was self-reported. Analyses were conducted overall and among those with stage 1 hypertension, defined by a mean SBP of 130-139 mmHg or DBP of 80-89 mmHg. In subgroups defined by diabetes, chronic kidney disease (CKD), and age at least 65 years, we estimated the proportion of United States adults with high ASCVDJournal of hypertensionPredicted cardiovascular risk for United States adults with diabetes, chronic kidney disease, and at least 65 years of age.PMC9259065K12 HD043451P20 GM109036R01 HL144773R01 HL139716Hardy STMuntner PSakhuja SAkinyelure OPWhelton PKJaeger BCBundy JDfalsePredicted cardiovascular risk for United States adults with diabetes, chronic kidney disease, and at least 65 years of age.<h4>Background</h4>The 2017 American College of Cardiology/American Heart Association blood pressure (BP) guideline recommends using 10-year predicted atherosclerotic cardiovascular disease (ASCVD) risk to guide decisions to initiate antihypertensive medication.<h4>Methods</h4>We included adults aged 40-79 years from the National Health and Nutrition Examination Survey 2013-2018 (n = 8803). We computed 10-year predicted ASCVD risk using the Pooled Cohort risk equations. Clinical CVD was self-reported. Analyses were conducted overall and among those with stage 1 hypertension, defined by a mean SBP of 130-139 mmHg or DBP of 80-89 mmHg. In subgroups defined by diabetes, chronic kidney disease (CKD), and age at least 65 years, we estimated the proportion of United States adults with high ASCVD2022-01-01T00:00:00Z2022 Jan2025-04-26T00:23:14.679Z2025-04-06T09:44:26.8ZS-EPMC92590653442001310.1097/HJH.000000000000298210.1097/hjh.0000000000002982