{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chen YT"],"funding":["National Institute of Arthritis and Musculoskeletal and Skin Diseases","Department of Physical Medicine &amp; Rehabilitation, University of Michigan","Dan Barry Research","ACL HHS","Rennes University Hospital","National Institute of Disability, Independent Living, and Rehabilitation Research, Administration for Community Living","University Hospitals HUGO","NIAMS NIH HHS","NIH"],"pagination":["3754-3765"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9259752"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["61(9)"],"pubmed_abstract":["<h4>Objectives</h4>This study used a qualitative approach to explore how people with SSc experience cognitive changes and how cognitive difficulties impact their functioning.<h4>Methods</h4>Four 90-min focus groups of adults with SSc and self-reported changes in cognition were recruited from a SSc research registry and targeted social media. A focus group guide elicited information from participants via open-ended questions. Content analysis was conducted using grounded theory methodology.<h4>Results</h4>There were 20 participants (mean age = 55.5 (11.4) years) comprising 16 (80%) females, 14 (70%) Caucasians, and 11 (55%) people with diffuse cutaneous SSc. Study themes included cognitive difficulties as part of daily life experience, impact of cognitive difficulties on daily life functioning, coping strategies and information seeking. Participants used different terms to describe their experience of cognitive difficulties, and most encountered deficits in short-term memory, language difficulties, decreased executive function, difficulties with concentration and focus, and slow processing speed. Participants expressed frustration with their cognitive difficulties and used coping strategies to lessen their impact. Participants were uncertain about the causes and wanted to understand factors contributing to cognitive difficulties as well as how to manage them.<h4>Conclusion</h4>Participants with SSc reported cognitive difficulties that had a substantial negative impact on their lives. Improved understanding of cognitive changes could subsequently facilitate development of relevant therapeutic interventions or educational programmes for symptom self-management to reduce impact of cognitive difficulties in people with SSc."],"journal":["Rheumatology (Oxford, England)"],"pubmed_title":["Cognitive difficulties in people with systemic sclerosis: a qualitative study."],"pmcid":["PMC9259752"],"funding_grant_id":["K24 AR063120","K24-AR-063129","90ARCP0003","R43 AR063129","G025678"],"pubmed_authors":["Devine A","Lescoat A","Chen YT","Khanna D","Murphy SL"],"additional_accession":[]},"is_claimable":false,"name":"Cognitive difficulties in people with systemic sclerosis: a qualitative study.","description":"<h4>Objectives</h4>This study used a qualitative approach to explore how people with SSc experience cognitive changes and how cognitive difficulties impact their functioning.<h4>Methods</h4>Four 90-min focus groups of adults with SSc and self-reported changes in cognition were recruited from a SSc research registry and targeted social media. A focus group guide elicited information from participants via open-ended questions. Content analysis was conducted using grounded theory methodology.<h4>Results</h4>There were 20 participants (mean age = 55.5 (11.4) years) comprising 16 (80%) females, 14 (70%) Caucasians, and 11 (55%) people with diffuse cutaneous SSc. Study themes included cognitive difficulties as part of daily life experience, impact of cognitive difficulties on daily life functioning, coping strategies and information seeking. Participants used different terms to describe their experience of cognitive difficulties, and most encountered deficits in short-term memory, language difficulties, decreased executive function, difficulties with concentration and focus, and slow processing speed. Participants expressed frustration with their cognitive difficulties and used coping strategies to lessen their impact. Participants were uncertain about the causes and wanted to understand factors contributing to cognitive difficulties as well as how to manage them.<h4>Conclusion</h4>Participants with SSc reported cognitive difficulties that had a substantial negative impact on their lives. Improved understanding of cognitive changes could subsequently facilitate development of relevant therapeutic interventions or educational programmes for symptom self-management to reduce impact of cognitive difficulties in people with SSc.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Aug","modification":"2026-06-03T18:38:55.128Z","creation":"2026-04-30T03:11:41.299Z"},"accession":"S-EPMC9259752","cross_references":{"pubmed":["35015836"],"doi":["10.1093/rheumatology/keac004"]}}