{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Azali MA"],"funding":["Universiti Sains Malaysia"],"pagination":["98"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9259773"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>The baculovirus expression vector system has been developed for expressing a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and vaccines. The availability of the SARS-CoV-2 genome sequence has enabled the synthesis of SARS-CoV2 proteins in a baculovirus-insect cell platform for various applications. The most cloned SARS-CoV-2 protein is the spike protein, which plays a critical role in SARS-CoV-2 infection. It is available in its whole length or as subunits like S1 or the receptor-binding domain (RBD). Non-structural proteins (Nsps), another recombinant SARS-CoV-2 protein generated by the baculovirus expression vector system (BEV), are used in the identification of new medications or the repurposing of existing therapies for the treatment "],"journal":["Journal, genetic engineering & biotechnology"],"pubmed_title":["Application of Baculovirus Expression Vector system (BEV) for COVID-19 diagnostics and therapeutics: a review."],"pmcid":["PMC9259773"],"funding_grant_id":["1001/PPSP/8011025"],"pubmed_authors":["Hussain FA","Mohamed S","Azali MA","Shamsuddin S","Johan MF","Harun A"],"additional_accession":[]},"is_claimable":false,"name":"Application of Baculovirus Expression Vector system (BEV) for COVID-19 diagnostics and therapeutics: a review.","description":"<h4>Background</h4>The baculovirus expression vector system has been developed for expressing a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and vaccines. The availability of the SARS-CoV-2 genome sequence has enabled the synthesis of SARS-CoV2 proteins in a baculovirus-insect cell platform for various applications. The most cloned SARS-CoV-2 protein is the spike protein, which plays a critical role in SARS-CoV-2 infection. It is available in its whole length or as subunits like S1 or the receptor-binding domain (RBD). Non-structural proteins (Nsps), another recombinant SARS-CoV-2 protein generated by the baculovirus expression vector system (BEV), are used in the identification of new medications or the repurposing of existing therapies for the treatment ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2025-04-04T12:40:42.564Z","creation":"2025-04-04T12:40:42.564Z"},"accession":"S-EPMC9259773","cross_references":{"pubmed":["35792966"],"doi":["10.1186/s43141-022-00368-7"]}}