{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Tao R"],"pubmed_abstract":["<h4>Introduction</h4>Phosphodiesterase type 5-inhibitors (PDE5is) are the first-line treatment for patients with diabetes mellitus-induced erectile dysfunction (DMED), however, some patients are non-responser to PDE5is. We performed a perspective, randomized, comparative study to explore the efficacy of low intensity extracorporeal shock wave treatment (Li-ESWT) combined with vacuum erectile device (VED) in the treatment of DMED patients who were unresponsive to PDE5is.<h4>Methods</h4>One hundred and five eligible patients were randomly divided into three groups: group A (VED), group B (Li-ESWT) and group C (VED plus Li-ESWT). Follow-up was conducted at 4 weeks, 8 weeks and 12 weeks after the end of treatment. The erectile function was estimated by the international index of erectile funct"],"journal":["Frontiers in endocrinology"],"pagination":["937958"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9259797"],"repository":["biostudies-literature"],"pubmed_title":["The Efficacy of Li-ESWT Combined With VED in Diabetic ED Patients Unresponsive to PDE5is: A Single-Center, Randomized Clinical Trial."],"pmcid":["PMC9259797"],"pubmed_authors":["Wu J","Yang J","Xiong L","Chen J","Zhou S","Jia C","Wang D","Xiang J","Ji J","Lv J","Li Y","Tang Q","Tao R"],"additional_accession":[]},"is_claimable":false,"name":"The Efficacy of Li-ESWT Combined With VED in Diabetic ED Patients Unresponsive to PDE5is: A Single-Center, Randomized Clinical Trial.","description":"<h4>Introduction</h4>Phosphodiesterase type 5-inhibitors (PDE5is) are the first-line treatment for patients with diabetes mellitus-induced erectile dysfunction (DMED), however, some patients are non-responser to PDE5is. We performed a perspective, randomized, comparative study to explore the efficacy of low intensity extracorporeal shock wave treatment (Li-ESWT) combined with vacuum erectile device (VED) in the treatment of DMED patients who were unresponsive to PDE5is.<h4>Methods</h4>One hundred and five eligible patients were randomly divided into three groups: group A (VED), group B (Li-ESWT) and group C (VED plus Li-ESWT). Follow-up was conducted at 4 weeks, 8 weeks and 12 weeks after the end of treatment. The erectile function was estimated by the international index of erectile funct","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-21T17:28:55.809Z","creation":"2022-07-22T07:50:23.616Z"},"accession":"S-EPMC9259797","cross_references":{"pubmed":["35813628"],"doi":["10.3389/fendo.2022.937958"]}}