{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Welch BM"],"funding":["NIEHS NIH HHS","NIH HHS"],"pagination":["895-905"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9274448"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["176(9)"],"pubmed_abstract":["<h4>Importance</h4>Phthalate exposure is widespread among pregnant women and may be a risk factor for preterm birth.<h4>Objective</h4>To investigate the prospective association between urinary biomarkers of phthalates in pregnancy and preterm birth among individuals living in the US.<h4>Design, setting, and participants</h4>Individual-level data were pooled from 16 preconception and pregnancy studies conducted in the US. Pregnant individuals who delivered between 1983 and 2018 and provided 1 or more urine samples during pregnancy were included.<h4>Exposures</h4>Urinary phthalate metabolites were quantified as biomarkers of phthalate exposure. Concentrations of 11 phthalate metabolites were standardized for urine dilution and mean repeated measurements across pregnancy were calculated.<h4>M"],"journal":["JAMA pediatrics"],"pubmed_title":["Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts."],"pmcid":["PMC9274448"],"funding_grant_id":["P01 ES009605","L40 ES032257","U24 ES028529","T32 ES007018","P30 ES010126","U24 ES028533","UH3 OD023251","P30 ES017885","R01 ES031591","P42 ES017198","R01 ES030078","P30 ES006096","P30 ES023513","R24 ES028533"],"pubmed_authors":["O'Brien KM","Wang C","Newman RB","Alshawabkeh AN","Rauh VA","Drobnis EZ","Pooled Phthalate Exposure and Preterm Birth Study Group","Watkins DJ","James-Todd T","Dabelea D","Messerlian C","Christenbury KE","Jukic AMZ","Weinberg CR","Cordero JF","Binder AM","Swan SH","Schmidt RJ","Welch BM","Factor-Litvak P","Hauser R","Eskenazi B","Wenzel AG","Bradman A","Barrett ES","Buckley JP","Calafat AM","Harley KG","Sparks AE","Rich DQ","Hertz-Picciotto I","Nguyen RHN","Aalborg J","Padmanabhan V","Starling AP","Keil AP","Ferguson KK","Weinberger B","Engel SM","Lanphear BP","Bush NR","Braun JM","Zota AR","Bloom MS","Holland N","Michels KB","Baird DD","Sathyanarayana S","McElrath TF","Meeker JD","Zhang Y","Yolton K","Wilcox AJ","Cantonwine DE","Herbstman JB","Rosen EM","Redmon JB"],"additional_accession":[]},"is_claimable":false,"name":"Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts.","description":"<h4>Importance</h4>Phthalate exposure is widespread among pregnant women and may be a risk factor for preterm birth.<h4>Objective</h4>To investigate the prospective association between urinary biomarkers of phthalates in pregnancy and preterm birth among individuals living in the US.<h4>Design, setting, and participants</h4>Individual-level data were pooled from 16 preconception and pregnancy studies conducted in the US. Pregnant individuals who delivered between 1983 and 2018 and provided 1 or more urine samples during pregnancy were included.<h4>Exposures</h4>Urinary phthalate metabolites were quantified as biomarkers of phthalate exposure. Concentrations of 11 phthalate metabolites were standardized for urine dilution and mean repeated measurements across pregnancy were calculated.<h4>M","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Sep","modification":"2026-05-07T17:54:05.963Z","creation":"2025-04-05T20:30:47.018Z"},"accession":"S-EPMC9274448","cross_references":{"pubmed":["35816333"],"doi":["10.1001/jamapediatrics.2022.2252"]}}