{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Retel Helmrich IRA"],"funding":["National Institute for Health Research (NIHR)","Seventh Framework Programme","Academy of Medical Sciences"],"pubmed_abstract":["<h4>Background</h4>Following traumatic brain injury (TBI), the clinical focus is often on disability. However, patients' perceptions of well-being can be discordant with their disability level, referred to as the 'disability paradox'. We aimed to examine the relationship between disability and health-related quality of life (HRQoL) following TBI, while taking variation in personal, injury-related and environment factors into account.<h4>Methods</h4>We used data from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury study. Disability was assessed 6 months post-injury by the Glasgow Outcome Scale-Extended (GOSE). HRQoL was assessed by the SF-12v2 physical and mental component summary scores and the Quality of Life after Traumatic Brain Injury overall sca"],"journal":["Journal of neurology, neurosurgery, and psychiatry"],"pagination":["jnnp-2021-326615"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9279746"],"repository":["biostudies-literature"],"pubmed_title":["Discrepancy between disability and reported well-being after traumatic brain injury."],"pmcid":["PMC9279746"],"funding_grant_id":["FP7/2007-2013","602150","ACF-2009-14-007","AMS-CSF4-Newcombe"],"pubmed_authors":["Radoi A","Williams G","Rossi S","Akerlund C","Golubovic J","Ziverte A","Rossaint R","Stanworth S","Posti JP","Galanaud D","Castano-Leon AM","Valeinis E","Perera N","Wijk RPJV","Schafer N","Stamatakis E","Steen GV","Lightfoot R","Kornaropoulos E","Vamos Z","Smielewski P","Jiang JY","Foks K","Polinder S","Citerio G","Rhodes J","Skandsen T","Zeiler FA","Grossi F","George P","Ripatti S","Ylen P","Esser P","Brinck V","Levi L","Manara A","Glocker B","Gravesteijn B","Haitsma I","Legrand V","Tamas V","McMahon C","Praag DV","Dixit A","Tamosuitis T","Carbonara M","Parizel PM","Rocka S","Mattern J","Sakowitz O","Coburn M","Andreassen L","Amrein K","Winzeck S","Dijck JV","Wang KK","Manley G","Vespa PM","Roise O","Rosenlund C","Depreitere B","Blaabjerg M","Majdan M","Gupta D","Audibert G","Menovsky T","Newcombe V","Taylor MS","Chevallard G","Benali H","Murray L","van Klaveren D","Ao BT","Helseth E","Nelson D","Vyvere TV","Tudora CM","Lecky F","Czeiter E","Voormolen D","Vulekovic P","Furmanov A","Curry N","Donoghue E","Takala R","Jones K","Dawes H","Đilvesi Đ","Czosnyka M","Mikolic A","Beauvais R","Younsi A","Richter S","Bellander BM","Lanyon L","Stevens R","Dreier J","Pomposo I","Bragge P","Rosenfeld JV","Olubukola O","Gantner D","Sanchez-Porras R","Tolias C","Beer R","Johnson F","CENTER-TBI participants and investigators","Zoerle T","Wolf S","Marechal H","Vajkoczy P","Peul W","Andelic N","Melegh B","Helbok R","Persona P","Maegele M","Vik A","Rambadagalla M","Calappi E","Chieregato A","Puybasset L","Tibboel D","Dahyot-Fizelier C","Gomez P","Kowark A","Cooper JD","Rusnak M","Brooker J","Wilson L","Martino C","Palotie A","Ortolano F","Kondziella D","Hecke WV","Gratz J","Sewalt C","Volovici V","Zelinkova V","Duliere GL","Verheyden J","Ragauskas A","Menon D","Richardson S","Gagliardo P","Laureys S","Vargiolu A","Boogert HD","Horton L","Naalt JV","Jagt MV","Van Veen E","Sorinola A","Jacobs B","Ezer E","Trapani T","Beretta L","Essen TAV","Theadom A","Ledoux D","Vega E","Thomas M","Azouvi P","Nieboer D","Sandor J","Steyerberg EW","Pirinen M","Stocchetti N","Cavallo S","Payen JF","Degos V","Koskinen LO","Calvi MR","Schou RF","Heugten CV","Cabeleira M","Azzolini ML","Sundstrom N","Schwendenwein E","Stewart W","Maas A","Vallance S","Berardino M","Brazinova A","Coles J","Negru A","Keyser V","Frisvold S","Roe C","Unterberg A","Covic A","Lejeune A","Velt K","Correia M","Gao G","Bullinger M","Caccioppola A","Hutchinson PJ","Wiegers E","Schoechl H","Ghuysen A","Schmidt S","Giga L","Perlbarg V","Schoonman G","Piippo-Karjalainen A","Haagsma JA","Retel Helmrich IRA","Belli A","Timmers M","Lozano GC","Kompanje E","Lefering R","Ercole A","Jankowski S","Huijben J","Bartels R","Buki A","Lagares A","Yang Z","Tenovuo O","Nyiradi J","Vilcinis R","Karan M","Lingsma H","Fabricius M","Rueckert D","Misset B","Feigin VL","Rosenthal G","Dark P","Ples H","Oresic M","Clusmann H","Raj R","Kovacs N","Brorsson C","Anke A","Sahuquillo J","Gruen RL","Rosand J","Maas AI","Jarrett M","Steinbuchel NV","Barzo P","Kolias AG","Corte FD","Muraleedharan V","Cameron P","Antoni A"],"additional_accession":[]},"is_claimable":false,"name":"Discrepancy between disability and reported well-being after traumatic brain injury.","description":"<h4>Background</h4>Following traumatic brain injury (TBI), the clinical focus is often on disability. However, patients' perceptions of well-being can be discordant with their disability level, referred to as the 'disability paradox'. We aimed to examine the relationship between disability and health-related quality of life (HRQoL) following TBI, while taking variation in personal, injury-related and environment factors into account.<h4>Methods</h4>We used data from the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury study. Disability was assessed 6 months post-injury by the Glasgow Outcome Scale-Extended (GOSE). HRQoL was assessed by the SF-12v2 physical and mental component summary scores and the Quality of Life after Traumatic Brain Injury overall sca","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2026-06-20T04:47:58.03Z","creation":"2026-06-20T03:10:26.834Z"},"accession":"S-EPMC9279746","cross_references":{"pubmed":["35537823"],"doi":["10.1136/jnnp-2021-326615"]}}