biostudies-literatureUnknown15(1)Huang KJ<h4>Background</h4>Ovarian clear cell carcinoma (OCCC) is the most common endometriosis-associated ovarian cancer. Ovarian endometriosis may present with atypical or malignant sonographic features and interfere with clinical judgment about whether definitive surgical intervention is required.<h4>Objective</h4>To compare the characteristics of endometrioma with atypical features and OCCC.<h4>Methods</h4>This study enrolled patients with pathologic diagnoses of either endometrioma or OCCC. For patients with endometrioma, only those with atypical features, defined as the presence of at least one of the following sonographic characteristics: cyst diameter of 10 ± 1 cm, multi-cystic lesions, any solid component or papillary structure, and blood flow of any degree, were included.<h4>Results</h4>Journal of ovarian research84https://www.ebi.ac.uk/biostudies/studies/S-EPMC9284754biostudies-literatureSonographic features differentiating early-stage ovarian clear cell carcinoma from endometrioma with atypical features.PMC9284754Huang KJWei LHWu CJLi YXChang WCSheu BCfalseSonographic features differentiating early-stage ovarian clear cell carcinoma from endometrioma with atypical features.<h4>Background</h4>Ovarian clear cell carcinoma (OCCC) is the most common endometriosis-associated ovarian cancer. Ovarian endometriosis may present with atypical or malignant sonographic features and interfere with clinical judgment about whether definitive surgical intervention is required.<h4>Objective</h4>To compare the characteristics of endometrioma with atypical features and OCCC.<h4>Methods</h4>This study enrolled patients with pathologic diagnoses of either endometrioma or OCCC. For patients with endometrioma, only those with atypical features, defined as the presence of at least one of the following sonographic characteristics: cyst diameter of 10 ± 1 cm, multi-cystic lesions, any solid component or papillary structure, and blood flow of any degree, were included.<h4>Results</h4>2022-01-01T00:00:00Z2022 Jul2025-04-04T21:41:18.196Z2025-04-04T21:41:18.196ZS-EPMC92847543583628810.1186/s13048-022-01019-8